Search results | J. Murrey Atkins Library

Title: IDENTIFICATION OF EPITHELIAL OVARIAN TUMOR SPECIFIC APTAMERS THAT BIND AND INTERNALIZE INTO TARGET CELLS
Author: Benedetto, Gregory
Date Created: 2015
Subjects--Topical: Chemistry, Biology
Description: New clinical tools that aid in the early diagnosis of ovarian malignancies will significantly help reduce mortality and improve current long-term survival rates. The objective of the work presented here was to identify ovarian tumor specific singl...

Title: MACROPHAGES EXPRESSING NEUROPILIN-1 AND BREAST TUMOR PROGRESSION
Author: Helms, Rachel
Date Created: 2015
Subjects--Topical: Biology
Description: Human breast carcinoma is the most commonly diagnosed cancer in women in the United States with patient mortality primarily resulting from metastasis of breast cancer cells to distant organs. Immune cells, including macrophages, are involved in ca...

Title: Microbial diversity and activity in the Nematostella vectensis holobiont : insights from 16S rRNA gene sequencing, isolate genomes, and a pilot-scale survey of gene expression
Author: Reitzel, Adam M., Har, Jia Y., Helbig, Tim
Date Created: 2015
Subjects--Topical: Gene expression, Biology
Description: We have characterized the molecular and genomic diversity of the microbiota of the starlet sea anemone Nematostella vectensis, a cnidarian model for comparative developmental and functional biology and a year-round inhabitant of temperate salt mar...

Title: Periostin and TGFBI in Breast Cancer Progression
Author: Phelps, Michelle
Date Created: 2015
Subjects--Topical: Biology, Cytology
Description: Dynamic interactions between cancer cells, supportive stromal cells, the extracellular matrix (ECM), and the immune system are critical to breast cancer progression. Periostin is an ECM protein correlated to poor outcomes in breast cancer. Periost...

Title: Phylogeny of echinoderm hemoglobins
Author: Janies, Daniel, Linchangco, Gregorio V., Jr.
Date Created: 2015
Subjects--Topical: Genomics, Biology
Description: Background Recent genomic information has revealed that neuroglobin and cytoglobin are the two principal lineages of vertebrate hemoglobins, with the latter encompassing the familiar myoglobin and alpha-globin/beta-globin tetramer hemoglobin, and ...

Title: Phylotranscriptomic analysis uncovers a wealth of tissue inhibitor of metalloproteinases variants in echinoderms
Author: Janies, Daniel, Clouse, Ronald M., Linchangco, Gregorio V., Jr.
Date Created: 2015
Subjects--Topical: Genomics, Biology
Description: Tissue inhibitors of metalloproteinases (TIMPs) help regulate the extracellular matrix (ECM) in animals, mostly by inhibiting matrix metalloproteinases (MMPs). They are important activators of mutable collagenous tissue (MCT), which have been exte...

Title: Pleiotropic effects on the transcriptome and genome of transgenic soybeans resulting from transgene integration and expression in seed tissue
Author: Lambirth, Kevin
Date Created: 2015
Subjects--Topical: Molecular biology, Biology, Bioinformatics
Description: The seeds of the common soybean (Glycine max) produce and store large amounts of protein, making them an appealing bioreactor for producing valuable recombinant proteins at high levels. However, the effects of accumulating recombinant protein at h...

Title: Rigidity emerges during antibody evolution in three distinct antibody systems: evidence from QSFR analysis of fab fragments
Author: Jacobs, Donald J., Li, Tong, Livesay, Dennis R.
Date Created: 2015
Subjects--Topical: Immunoglobulins, Biology
Description: The effects of somatic mutations that transform polyspecific germline (GL) antibodies to affinity mature (AM) antibodies with monospecificity are compared among three GL-AM Fab pairs. In particular, changes in conformational flexibility are assess...

Title: Sex-specific and developmental expression of dmrt genes in the starlet sea anemone, Nematostella vectensis
Author: Reitzel, Adam M., Traylor-Knowles, Nikki G., Kane, Eric G.
Date Created: 2015
Subjects--Topical: Evolution (Biology), Biology
Description: Background: The molecular mechanisms underlying sex determination and differentiation in animals are incredibly diverse. The Dmrt (doublesex and mab-3 related transcription factor) gene family is an evolutionary ancient group of transcription fact...

Title: TISSUE SPECIFIC RESPONSES OF THE ESTUARINE BIVALVE SPECIES CRASSOSTREA VIRGINICA AND GEUKENSIA DEMISSA TO HYPOXIA
Author: Khan, Bushra
Date Created: 2015
Subjects--Topical: Biology
Description: Aquatic ecosystems are exposed to multiple stressors simultaneously. Many estuarine sites which show diurnal dissolved oxygen (DO) and pH fluctuations are also exposed to metals which can be toxic to marine organisms. Bivalve mollusks serve as goo...

Title: The Relationship of Reproductive Hormones and Host Susceptibility to the Opportunistic Pathogen, Vibrio vulnificus
Author: McKee, Leslie
Date Created: 2015
Subjects--Topical: Biology, Microbiology, Endocrinology
Description: It is commonly found that males show a higher susceptibility to infectious diseases. While the underlying mechanism for this sex difference is not fully understood, one significant contributing attribute is the presence of specific sex hormones- e...