Search results
- Title
- A STRUCTURAL AND FUNCTIONAL ANALYSIS OF NEMATOSTELLA VECTENSIS MAJOR INTRINSIC PROTEINS
- Author
- Taylor, Jonathon
- Date Created
- 2020
- Subjects--Topical
- Biology, Cytology, Evolutionary developmental biology
- Description
- There is currently a major gap in understanding the physiological processes of tissue grade animals from early diverging phyla, particularly within the context of the molecular mechanisms in response to osmotic variation. A key protein family esse...
- Title
- A subterminal growth zone at arm tip likely underlies life-long indeterminate growth in brittle stars
- Author
- Janies, Daniel, Machado, Denis Jacob, Reid, Robert, Kofsky, Janice
- Date Created
- 2022
- Subjects--Topical
- Genomics, Biology
- Description
- Background Echinoderms are a phylum of marine invertebrates with close phylogenetic relationships to chordates. Many members of the phylum Echinodermata are capable of extensive post-traumatic regeneration and life-long indeterminate growth. Diffe...
- Title
- ASSESSING COMPARATIVE FUNCTIONS FOR THE BZIP TRANSCRIPTION FACTOR NFE2 IN NEMATOSTELLA VECTENSIS
- Author
- Clegg, Devin
- Date Created
- 2020
- Subjects--Topical
- Biology
- Description
- The bZIP gene superfamily is a family of transcription factors that have gone through multiple duplication events within bilaterians, specifically in vertebrates. This has led to multiple paralogs in each bZIP family while early diverging phyla ha...
- Title
- Active Notch signaling is required for arm regeneration in a brittle star
- Author
- Janies, Daniel, Machado, Denis Jacob, Reid, Robert
- Date Created
- 2020
- Subjects--Topical
- Genomics, Biology
- Description
- Cell signaling pathways play key roles in coordinating cellular events in development. The Notch signaling pathway is highly conserved across all multicellular animals and is known to coordinate a multitude of diverse cellular events, including pr...
- Title
- Assessing the impact of temperature on population-specific gene expression of a model estuarine cnidarian, Nematostella vectensis
- Author
- Klock, Amy
- Date Created
- 2020
- Subjects--Topical
- Biology
- Description
- Temperature is a critical environmental factor that affects all living organisms. Climate change is resulting in rising global temperatures with marine environments being especially vulnerable. My study aimed to elucidate the temperature-dependent...
- Title
- CELLULAR BIOMARKER RESPONSES OF THE ASIAN CLAM, CORBICULA FLUMINEA, NEAR A COAL ASH POND
- Author
- Thomason, Travis
- Date Created
- 2018
- Subjects--Topical
- Biology
- Description
- The storage of coal combustion residuals (CCR) in aquatic surface impoundments has been a common practice across the United States for decades. Typically these aquatic surface impoundments are designed to allow the upper portion of the ash-basin w...
- Title
- Calculating ensemble averaged descriptions of protein rigidity without sampling
- Author
- Jacobs, Donald J., Gonzalez, Luis C., Wang, Hui, Livesay, Dennis R.
- Date Created
- 2012
- Subjects--Topical
- Biology, Proteins
- Description
- Previous works have demonstrated that protein rigidity is related to thermodynamic stability, especially under conditions that favor formation of native structure. Mechanical network rigidity properties of a single conformation are efficiently cal...
- Title
- Characterizing a New Regulator of the ATR Signaling Pathway
- Author
- Biller, Megan
- Date Created
- 2022
- Subjects--Topical
- Molecular biology, Biology
- Description
- Cellular responses to DNA damage and replication stress are coordinated by an intricate network of repair pathways known as the DNA damage response (DDR). Central to the DDR is the essential kinase ataxia telangiectasia mutated and Rad3-related (A...
- Title
- Characterizing the diversity of heat shock proteins in Nematostella vectensis and Saccharomyces cerevisiae
- Author
- Alexander, William, Reitzel, Adam M., Truman, Andrew
- Date Created
- 2022
- Subjects--Topical
- Heat shock proteins, Biology
- Description
- Heat shock proteins (HSPs) are a highly conserved family of proteins critical to both environmental stress response and cellular function under normal conditions. More specifically HSPs are chaperone proteins that work to refold other misfolded pr...
- Title
- Chemoenzymatic preparation of a Campylobacter jejuni lipid-linked heptasaccharide on an azide-linked polyisoprenoid
- Author
- Reid, Amanda J., Erickson, Katelyn M., Hazel, Joseph M., Troutman, Jerry M.
- Date Created
- 2023
- Subjects--Topical
- Biology, Carbohydrates
- Description
- Complex poly- and oligosaccharides on the surface of bacteria provide a unique fingerprint to different strains of pathogenic and symbiotic microbes that could be exploited for therapeutics or sensors selective for specific glycans. To discover re...
- Title
- Content and sentiment surveillance (CSI) : A critical component for modeling modern epidemics
- Author
- Janies, Daniel, Chen, Shi, Zhang, Dongsong
- Date Created
- 2023
- Subjects--Topical
- Communicable diseases, Biology
- Description
- Comprehensive surveillance systems are the key to provide accurate data for effective modeling. Traditional symptom-based case surveillance has been joined with recent genomic, serologic, and environment surveillance to provide more integrated dis...
- Title
- Convergent shifts in host-associated microbial communities across environmentally elicited phenotypes
- Author
- Reitzel, Adam M., Carrier, Tyler J.
- Date Created
- 2018
- Subjects--Topical
- Evolution (Biology), Biology
- Description
- Morphological plasticity is a genotype-by-environment interaction that enables organisms to increase fitness across varying environments. Symbioses with diverse microbiota may aid in acclimating to this variation, but whether the associated bacter...
- Title
- Cranial Capacity Variation of Pleistocene Homo and Possible Speciation Events
- Author
- Hudock, Autumn
- Date Created
- 2021
- Subjects--Topical
- Biology, Paleontology, Evolutionary developmental biology
- Description
- The field of paleoanthropology is tasked with studying the morphology of extinct hominins using fossilized remains. To study the evolution of the human brain, researchers use endocast data derived from fossil skulls, in order to assess when and ho...
- Title
- DNA extraction method plays a significant role when defining bacterial community composition in the marine invertebrate Echinometra mathaei
- Author
- Reitzel, Adam M., Ketchum, Remi, Carrier, Tyler J.
- Date Created
- 2018
- Subjects--Topical
- Bacteria, Biology
- Description
- The microbial assemblages of marine organisms play fundamental biological roles in their eukaryotic hosts. Studies aimed at characterizing this diversity have increased over the last decade and with the availability of high-throughput sequencing, ...
- Title
- Daily cycle in oxygen consumption by the sea anemone Nematostella vectensis Stephenson
- Author
- Reitzel, Adam M., Maas, Amy E., Jones, Ian T.
- Date Created
- 2016
- Subjects--Topical
- Gene expression, Biology
- Description
- In bilaterian animals, the circadian clock is intimately involved in regulating energetic metabolism. Although cnidarians exhibit diel behavioral rhythms including cycles in locomotor activity, tentacle extension and spawning, daily cycles in cnid...
- Title
- Developmental and light-entrained expression of melatonin and its relationship to the circadian clock in the sea anemone Nematostella vectensis
- Author
- Reitzel, Adam M., Peres, Rafael, Passamaneck, Yale
- Date Created
- 2014
- Subjects--Topical
- Gene expression, Biology
- Description
- Background: The primary hormone of the vertebrate pineal gland, melatonin, has been identified broadly throughout the eukaryotes. While the role for melatonin in cyclic behavior via interactions with the circadian clock has only been reported in v...
- Title
- Developmental expression of germline- and sex determination-related genes in the ctenophore Mnemiopsis leidyi
- Author
- Reitzel, Adam M., Pang, Kevin, Martindale, Mark Q.
- Date Created
- 2016
- Subjects--Topical
- Evolution (Biology), Biology
- Description
- Background: An essential developmental pathway in sexually reproducing animals is the specification of germ cells and the differentiation of mature gametes, sperm and oocytes. The germline genes vasa, nanos and piwi are commonly identified in prim...
- Title
- Diel patterning in the bacterial community associated with the sea anemone Nematostella vectensis
- Author
- Reitzel, Adam M., Leach, Whitney B., Carrier, Tyler J.
- Date Created
- 2019
- Subjects--Topical
- Gene expression, Biology
- Description
- Microbes can play an important role in the physiology of animals by providing essential nutrients, inducing immune pathways, and influencing the specific species that compose the microbiome through competitive or facilitatory interactions. The com...
- Title
- Dry Preservation of Germinal Vesicles: Development of a New Formulation to Preserve DNA Integrity Under Adverse Environmental Conditions
- Author
- Orozco Cabral, Joseph
- Date Created
- 2022
- Subjects--Topical
- Biology, Bioengineering
- Description
- Advances in the cryopreservation of genetic material has revolutionized human reproductive medicine and animal conservation efforts. Despite many successes, oocytes have been more challenging to cryopreserve than sperm. Their large size makes it d...
- Title
- ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
- Author
- Okwei, Elleansar
- Date Created
- 2016
- Subjects--Topical
- Chemistry, Biology, Biochemistry
- Description
- The fight against bacterial infection is one of the most important branches of modern medicine. Due to the emergence of strains of antibiotic-resistant bacteria, researchers have been presented with complex challenges in an effort to combat these ...