Search results | J. Murrey Atkins Library

Title: VPS501, A NOVEL SNX-BAR PROTEIN INVOLVED IN AUTOPHAGY
Author: goyal, Shreya
Date Created: 2021
Subjects--Topical: Biochemistry, Cytology, Molecular biology
Description: ABSTRACTCareful control of intracellular signaling pathways plays an important role in a cell’s ability to maintain stable internal conditions in the face of an ever-changing extracellular environment. This is particularly true as it relates to th...

Title: Understanding and overcoming limitations of vesicular stomatitis virus as an oncolytic agent against pancreatic ductal adenocarcinoma
Author: Hastie, Eric
Date Created: 2014
Subjects--Topical: Virology, Biology
Description: Vesicular stomatitis virus (VSV) is a prototypic nonsegmented negative-strand RNA virus. Lack of preexisting immunity against VSV, inherent oncotropism, and genetic malleability make VSV a widely used platform for vaccine, oncolytic, and gene ther...

Title: Understanding The Role of Pancreatic Ductal Adenocarcinoma Chemoresistance and Intertumoral Heterogeneity on Vesicular Stomatitis Virus-based Oncolytic Therapy
Author: Goad, Dakota
Date Created: 2023
Subjects--Topical: Biology, Virology, Biomedical engineering
Description: Viruses are obligate intracellular parasites that are now being increasingly harnessed as therapeutics for human diseases. Investigating different cellular factors and processes that affect viral infection allows us to improve the efficacy of viru...

Title: Understanding Salt Adaptation in Sand Beans (Strophostyles helvola)
Author: Zuelsdorf, Christine
Date Created: 2018
Subjects--Topical: Biology
Description: Soil salinity is one of the major environmental factors causing crop yield loss worldwide. Different plants develop diverse salinity tolerance mechanisms to manage such a detrimental abiotic stress. The sand bean (Strophostyles helvola), a wild re...

Title: Understanding Chaperone interactions in disease
Author: Nitika
Date Created: 2021
Subjects--Topical: Molecular biology, Biochemistry, Cytology
Description: The correct folding of proteins after synthesis and stress-promoted denaturation is critical for cell viability in all organisms. The Hsp70 molecular chaperone is a key player in proteostasis, deciding which proteins are foldable and which are too...

Title: Towards The Dry Preservation of Feline Sperm: The Effect Of Dehydration On DNA, Centrosomal Function, And Embryo Development
Author: Patrick, Jennifer
Date Created: 2016
Subjects--Topical: Biology
Description: The current gold standard for gamete preservation is cryogenic storage. Dry preservation is an attractive alternative, eliminating the need for refrigeration, reducing storage maintenance costs, and providing logistical flexibility for shipping. T...

Title: Topoisomerase II Inhibitors Induce an Illegitimate Genome Rearrangement Common in Infant Leukemia
Author: Bariar, Bhawana
Date Created: 2013
Subjects--Topical: Molecular biology
Description: Infant acute leukemias account for ~30% of all malignancy seen in childhood across the Western world. They are aggressive and characterized by rapid onset shortly after birth. The majority of these have rearrangements involving the MLL (mixed line...

Title: The role of the sex steroids in regulation of physical activity levels in mice
Author: Bowen, Robert
Date Created: 2010
Subjects--Topical: Kinesiology, Physiology
Description: Low physical activity (PA) levels are associated with many chronic diseases and place a massive burden on the health care system. The extrinsic environment has been suggested to regulate activity levels, but an increasing prevalence of physical in...

Title: The role of the dopaminergic system in the regulation of physical activity in mice
Author: Knab, Amy
Date Created: 2009
Subjects--Topical: Molecular biology, Genetics, Physiology
Description: Physical activity (PA) is important to human health, and the genetic and biological regulating factors of physical activity are only beginning to be understood. The dopamine (DA) system has been shown to regulate motivation, and locomotor behavior...

Title: The influence of wastewater treatment on community dynamics among antibiotic-resistant bacteria during treatment, stream release, and biosolids land application.
Author: Sorgen, Alicia
Date Created: 2020
Subjects--Topical: Microbiology, Bioinformatics, Ecology
Description: Wastewater treatment plants (WWTP) are a key link between anthropogenic activity and the environment, facilitating the development and horizontal transfer of antibiotic resistance among populations of commensal environmental microorganisms and cli...

Title: The induction of type-I interferon responses in primary osteoblasts following staphylococcus aureus infection
Author: Furr, Kelli
Date Created: 2022
Subjects--Topical: Biology
Description: Osteomyelitis is a serious bacterial infection of bone that is associated with progressive inflammatory tissue damage. This condition commonly affects the long bones of children along with the vertebrae and pelvis of adults. Staphylococcus aureus,...

Title: The in-vivo Evolution of Burkholderia multivorans in a Cystic Fibrosis patient
Author: Harrison, Sarah
Date Created: 2021
Subjects--Topical: Biology, Microbiology, Bioinformatics
Description: ABSTRACT Burkholderia multivorans is an opportunistic pathogen that poses a health risk to patients with cystic fibrosis (CF). The use of broad-range antibiotics to combat chronic bacterial lung infections has led to the evolution of antibiotic-re...

Title: The ecology of C-genotype and E-genotype strains of the bacterium Vibrio vulnificus and their interactions with the American oyster Crassostrea virginica
Author: Froelich, Brett
Date Created: 2012
Subjects--Topical: Biology, Microbiology
Description: Vibrio vulnificus is a pathogenic bacterium, routinely found in waters of estuarine environments as part of the normal microflora. This organism can be divided into two genotypes, a C-type associated with clinical isolation, and an E-type associat...

Title: The Role of the Cell Cycle in Karlodinium veneficum Toxicity: Tools and Predictions From the Laboratory
Author: Broemsen, Erik
Date Created: 2023
Subjects--Topical: Biology, Marine biology, Microbiology
Description: The toxic dinoflagellate Karlodinium veneficum forms blooms in estuaries worldwide. These blooms are often associated with severe fish mortalities that are largely caused by production of karlotoxins. The toxicity of these blooms can vary between ...

Title: The Role of Metformin on Non-Small Cell Lung Cancer Progression and Skeletal Muscle Health.
Author: Bond, Nicole
Date Created: 2021
Subjects--Topical: Molecular biology, Kinesiology
Description: Lung cancer is the second most common cancer and maintains a relatively small survival rate (~20%). Non-Small Cell Lung Cancer (NSCLC) makes up 80-85% of all lung cancer diagnoses. Lung cancer patients routinely undergo surgical procedures, chemot...

Title: The Role of Isometric Exercise Training on Reductions in Resting Blood Pressure: Human Trials and the Influence of Peripheral Vasoactive and Inflammatory Biomarkers
Author: Gordon, Benjamin
Date Created: 2012
Subjects--Topical: Biology, Kinesiology, Physiology
Description: Approximately 1 billion people worldwide and ~87 million adults in the United States alone are affected by hypertension [HTN: high blood pressure (HBP)]. Primary treatment avenues for HBP management include lifestyle modification (e.g. diet, exerc...

Title: The Relationship of Reproductive Hormones and Host Susceptibility to the Opportunistic Pathogen, Vibrio vulnificus
Author: McKee, Leslie
Date Created: 2015
Subjects--Topical: Biology, Microbiology, Endocrinology
Description: It is commonly found that males show a higher susceptibility to infectious diseases. While the underlying mechanism for this sex difference is not fully understood, one significant contributing attribute is the presence of specific sex hormones- e...

Title: The Prognostic Value of Relative Grip Strength in Assessing Hypertension Risk
Author: Gaillard, Ebony
Date Created: 2023
Subjects--Topical: Kinesiology, Biology, Public health
Description: More than 1.3 billion people are affected by hypertension (HTN) globally. Research has shown that Black women have the highest prevalence of hypertension worldwide compared to women of other racial/ethnic backgrounds. Although attempts have been m...

Title: The Potential for Genistein, a Topoisomerase II Inhibitor, to Induce Inter-Chromosomal Homologous Recombination.
Author: French, Caroline
Date Created: 2023
Subjects--Topical: Molecular biology
Description: Maintenance of genome integrity is important for preventing mutagenic events and preserving overall cell functionality. DNA damaging agents induce DNA double strand breaks (DSBs) that are repaired through repair pathways non-homologous end-joining...

Title: The Moon Jellyfish (Aurelia aurita): A Prospective Pelagic and Estuarine Bioindicator
Author: Lowder, Matthew
Date Created: 2016
Subjects--Topical: Biology, Environmental sciences, Toxicology
Description: Due in part to the complexity of scyphozoan life histories, slight changes in environmental factors can have an effect on fecundity, growth & development and population fluctuations. Anthropogenic activities have been suggested as a major cause of...