Search results
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Title
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Molecular function recognition by supervised projection pursuit machine learning
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Author
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Jacobs, Donald J., Grear, Tyler, Avery, Chris, Patterson, John
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Date Created
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2021
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Subjects--Topical
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Molecular biology, Pharmaceutical chemistry
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Description
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Identifying mechanisms that control molecular function is a significant challenge in pharmaceutical science and molecular engineering. Here, we present a novel projection pursuit recurrent neural network to identify functional mechanisms in the co...
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Title
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Understanding Chaperone interactions in disease
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Author
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Nitika
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Date Created
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2021
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Subjects--Topical
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Molecular biology, Biochemistry, Cytology
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Description
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The correct folding of proteins after synthesis and stress-promoted denaturation is critical for cell viability in all organisms. The Hsp70 molecular chaperone is a key player in proteostasis, deciding which proteins are foldable and which are too...
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Title
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VPS501, A NOVEL SNX-BAR PROTEIN INVOLVED IN AUTOPHAGY
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Author
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goyal, Shreya
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Date Created
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2021
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Subjects--Topical
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Biochemistry, Cytology, Molecular biology
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Description
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ABSTRACTCareful control of intracellular signaling pathways plays an important role in a cell’s ability to maintain stable internal conditions in the face of an ever-changing extracellular environment. This is particularly true as it relates to th...