Search results
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Title
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Comparative phylogenetic studies on Schistosoma japonicum and its snail intermediate host Oncomelania hupensis : origins, dispersal and coevolution
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Author
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Attwood, Stephen W., Ibaraki, Motomu, Saitoh, Yasuhide, Janies, Daniel
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Subjects--Topical
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Parasites, Coevolution, Public health
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Description
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Schistosoma japonicum causes major public health problems in China and the Philippines; this parasite, which is transmitted by freshwater snails of the species Oncomelania hupen- sis, causes the disease intestinal schistosomiasis in humans and cat...
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Title
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Content and sentiment surveillance (CSI) : A critical component for modeling modern epidemics
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Author
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Janies, Daniel, Chen, Shi, Zhang, Dongsong
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Date Created
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2023
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Subjects--Topical
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Communicable diseases, Biology
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Description
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Comprehensive surveillance systems are the key to provide accurate data for effective modeling. Traditional symptom-based case surveillance has been joined with recent genomic, serologic, and environment surveillance to provide more integrated dis...
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Title
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Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia : implication for malaria diagnosis
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Author
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Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background Rapid diagnostic tests (RDTs) targeting histidine rich protein 2(HRP2) are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the PfHRP3 antigen contributes to the detection of P. falciparum infections in PfH...
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Title
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EchinoDB, an application for comparative transcriptomics of deeply-sampled clades of echinoderms
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Author
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Janies, Daniel, Witter, Zachary, Linchangco, Gregorio V., Jr.
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Date Created
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2016
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Subjects--Topical
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Genomics, Biology
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Description
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Background: One of our goals for the echinoderm tree of life project (http://echinotol.org) is to identify orthologs suitable for phylogenetic analysis from next-generation transcriptome data. The current dataset is the largest assembled for echin...
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Title
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Exploring feasibility of multivariate deep learning models in predicting COVID-19 epidemic
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Author
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Thill, Jean-Claude, Janies, Daniel, Chen, Shi, Paul, Rajib
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Date Created
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2021
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Subjects--Topical
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Deep learning (Machine learning), COVID-19 (Disease)
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Description
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Background: Mathematical models are powerful tools to study COVID-19. However, one fundamental challenge in current modeling approaches is the lack of accurate and comprehensive data. Complex epidemiological systems such as COVID-19 are especially...
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Title
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Genetic diversity of Anopheles stephensi in Ethiopia provides insight into patterns of spread
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background: The recent detection of the South Asian malaria vector Anopheles stephensi in the Horn of Africa (HOA) raises concerns about the impact of this mosquito on malaria transmission in the region. Analysis of An. stephensi genetic diversity...
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Title
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Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia : its impact on the performance of malaria rapid diagnostic tests
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Author
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Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background Rapid diagnostic tests (RDT) are commonly used for the diagnosis of malaria caused by Plasmodium falciparum. However, false negative results of RDT caused by genetic variation of P. falciparum histidine-rich protein 2 and 3 genes (pfhrp...
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Title
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Geographical distribution of Anopheles stephensi in eastern Ethiopia
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2020
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background The recent detection of the South Asian malaria vector Anopheles stephensi in Ethiopia and other regions in the Horn of Africa has raised concerns about its potential impact on malaria transmission. We report here the findings of a surv...
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Title
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Insecticide resistance in Anopheles stephensi in Somali Region, eastern Ethiopia
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2020
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background The movement of malaria vectors into new areas is a growing concern in the efforts to control malaria. The recent report of Anopheles stephensi in eastern Ethiopia has raised the necessity to understand the insecticide resistance status...
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Title
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Integration of phylogenomics and molecular modeling reveals lineage-specific diversification of toxins in scorpions
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Author
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Janies, Daniel, Rush, Nathaniel, Witter, Zachary, Williams, John
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Date Created
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2018
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Subjects--Topical
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Genomics, Biology
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Description
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Scorpions have evolved a variety of toxins with a plethora of biological targets, but characterizing their evolution has been limited by the lack of a comprehensive phylogenetic hypothesis of scorpion relationships grounded in modern, genome-scale...
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Title
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Modeling Plasmodium falciparum diagnostic test sensitivity using machine learning with histidine-rich protein 2 variants
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Author
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Ford, Colby, Janies, Daniel, Alemayehu, Gezahegn, Lo, Eugenia, Blackburn, Kayla, Lopez, Karen, Dieng, Cheikh Cambel, Golassa, Lemu
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Subjects--Topical
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Malaria, Plasmodium falciparum
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Description
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Malaria, predominantly caused by Plasmodium falciparum, poses one of largest and most durable health threats in the world. Previously, simplistic regression-based models have been created to characterize malaria rapid diagnostic test performance, ...
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Title
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Patch dynamics modeling framework from pathogens' perspective : Unified and standardized approach for complicated epidemic systems
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Author
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Janies, Daniel, Chen, Shi, Lo, Eugenia, Dulin, Michael
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Date Created
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2020
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Subjects--Topical
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Communicable diseases, Biology
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Description
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Mathematical models are powerful tools to investigate, simulate, and evaluate potential interventions for infectious diseases dynamics. Much effort has focused on the Susceptible-Infected-Recovered (SIR)-type compartment models. These models consi...
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Title
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Phylogeny of echinoderm hemoglobins
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Author
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Janies, Daniel, Linchangco, Gregorio V., Jr.
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Date Created
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2015
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Subjects--Topical
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Genomics, Biology
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Description
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Background Recent genomic information has revealed that neuroglobin and cytoglobin are the two principal lineages of vertebrate hemoglobins, with the latter encompassing the familiar myoglobin and alpha-globin/beta-globin tetramer hemoglobin, and ...