Search results
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Title
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Comparative phylogenetic studies on Schistosoma japonicum and its snail intermediate host Oncomelania hupensis : origins, dispersal and coevolution
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Author
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Attwood, Stephen W., Ibaraki, Motomu, Saitoh, Yasuhide, Janies, Daniel
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Subjects--Topical
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Parasites, Coevolution, Public health
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Description
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Schistosoma japonicum causes major public health problems in China and the Philippines; this parasite, which is transmitted by freshwater snails of the species Oncomelania hupen- sis, causes the disease intestinal schistosomiasis in humans and cat...
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Title
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Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia : implication for malaria diagnosis
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Author
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Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background Rapid diagnostic tests (RDTs) targeting histidine rich protein 2(HRP2) are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the PfHRP3 antigen contributes to the detection of P. falciparum infections in PfH...
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Title
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FLAVi : an enhanced annotator for viral genomes of Flaviviridae
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Author
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Machado, Denis Jacob, Schneider, Adriano, Guirales, Sayal, Janies, Daniel
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Subjects--Topical
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Viruses, Phylogeny
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Description
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Responding to the ongoing and severe public health threat of viruses of the family Flaviviridae, including dengue, hepatitis C, West Nile, yellow fever, and Zika, demands a greater understanding of how these viruses emerge and spread. Updated phyl...
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Title
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Fundamental evolution of all Orthocoronavirinae including three deadly lineages descendent from Chiroptera-hosted coronaviruses : SARS-CoV, MERS-CoV and SARS-CoV-2
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Author
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Machado, Denis Jacob, Scott, Rachel, Guirales, Sayal, Janies, Daniel
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Subjects--Topical
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Coronaviruses, SARS (Disease), MERS (Disease), COVID-19 (Disease)
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Description
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The severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in humans in 2002. Despite reports showing Chiroptera as the original animal reservoir of SARS-CoV, many argue that Carnivora-hosted viruses are the most likely origin. The emerg...
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Title
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Fundamentals of genomic epidemiology, lessons learned from the coronavirus disease 2019 (COVID-19) pandemic, and new directions
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Author
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Machado, Denis Jacob, White, Richard Allen, III, Kofsky, Janice, Janies, Daniel
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Subjects--Topical
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COVID-19 (Disease), Epidemiology
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Description
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The coronavirus disease 2019 (COVID-19) pandemic was one of the significant causes of death worldwide in 2020. The disease is caused by severe acute coronavirus syndrome (SARS) coronavirus 2 (SARS-CoV-2), an RNA virus of the subfamily Orthocoronav...
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Title
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Genetic diversity of Anopheles stephensi in Ethiopia provides insight into patterns of spread
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background: The recent detection of the South Asian malaria vector Anopheles stephensi in the Horn of Africa (HOA) raises concerns about the impact of this mosquito on malaria transmission in the region. Analysis of An. stephensi genetic diversity...
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Title
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Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia : its impact on the performance of malaria rapid diagnostic tests
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Author
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Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background Rapid diagnostic tests (RDT) are commonly used for the diagnosis of malaria caused by Plasmodium falciparum. However, false negative results of RDT caused by genetic variation of P. falciparum histidine-rich protein 2 and 3 genes (pfhrp...
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Title
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Geographical distribution of Anopheles stephensi in eastern Ethiopia
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2020
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background The recent detection of the South Asian malaria vector Anopheles stephensi in Ethiopia and other regions in the Horn of Africa has raised concerns about its potential impact on malaria transmission. We report here the findings of a surv...
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Title
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Insecticide resistance in Anopheles stephensi in Somali Region, eastern Ethiopia
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2020
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background The movement of malaria vectors into new areas is a growing concern in the efforts to control malaria. The recent report of Anopheles stephensi in eastern Ethiopia has raised the necessity to understand the insecticide resistance status...
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Title
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Modeling Plasmodium falciparum diagnostic test sensitivity using machine learning with histidine-rich protein 2 variants
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Author
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Ford, Colby, Janies, Daniel, Alemayehu, Gezahegn, Lo, Eugenia, Blackburn, Kayla, Lopez, Karen, Dieng, Cheikh Cambel, Golassa, Lemu
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Subjects--Topical
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Malaria, Plasmodium falciparum
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Description
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Malaria, predominantly caused by Plasmodium falciparum, poses one of largest and most durable health threats in the world. Previously, simplistic regression-based models have been created to characterize malaria rapid diagnostic test performance, ...
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Title
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Sequence-based identification of Anopheles species in eastern Ethiopia
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2019
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background: The recent finding of a typically non-African Anopheles species in eastern Ethiopia emphasizes the need for detailed species identification and characterization for effective malaria vector surveillance. Molecular approaches increase t...
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Title
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Updated phylogeny of chikungunya virus suggests lineage-specific RNA architecture
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Author
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Janies, Daniel
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Date Created
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2019
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Subjects--Topical
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Communicable diseases, Biology
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Description
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Chikungunya virus (CHIKV), a mosquito-borne alphavirus of the family Togaviridae, has recently emerged in the Americas from lineages from two continents: Asia and Africa. Historically, CHIKV circulated as at least four lineages worldwide with both...
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Title
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Zika virus : medical countermeasure development challenges
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Author
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Janies, Daniel, Damodaran, Lambodhar, Schneider, Adriano
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Date Created
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2016
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Subjects--Topical
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Communicable diseases, Zika virus
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Description
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Introduction Reports of high rates of primary microcephaly and Guillain-Barre syndrome associated with Zika virus infection in French Polynesia and Brazil have raised concerns that the virus circulating in these regions is a rapidly developing neu...