Search results
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Title
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A new strategy to infer circularity applied to four new complete frog mitogenomes
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Author
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Machado, Denis Jacob, Janies, Daniel, Brouwer, Cory, Grant, Taran
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Date Created
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2018
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Subjects--Topical
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Genomics, Amphibians, Bioinformatics
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Description
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We applied a novel strategy to infer sequence circularity and complete assembly of four mitochondrial genomes (mitogenomes) of the frog families Bufonidae (Melanophryniscus moreirae), Dendrobatidae (Hyloxalus subpunctatus and Phyllobates terribili...
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Title
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Active Notch signaling is required for arm regeneration in a brittle star
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Author
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Janies, Daniel, Machado, Denis Jacob, Reid, Robert
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Date Created
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2020
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Subjects--Topical
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Genomics, Biology
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Description
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Cell signaling pathways play key roles in coordinating cellular events in development. The Notch signaling pathway is highly conserved across all multicellular animals and is known to coordinate a multitude of diverse cellular events, including pr...
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Title
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Comparative phylogenetic studies on Schistosoma japonicum and its snail intermediate host Oncomelania hupensis : origins, dispersal and coevolution
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Author
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Attwood, Stephen W., Ibaraki, Motomu, Saitoh, Yasuhide, Janies, Daniel
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Subjects--Topical
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Parasites, Coevolution, Public health
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Description
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Schistosoma japonicum causes major public health problems in China and the Philippines; this parasite, which is transmitted by freshwater snails of the species Oncomelania hupen- sis, causes the disease intestinal schistosomiasis in humans and cat...
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Title
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Content and sentiment surveillance (CSI) : A critical component for modeling modern epidemics
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Author
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Janies, Daniel, Chen, Shi, Zhang, Dongsong
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Date Created
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2023
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Subjects--Topical
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Communicable diseases, Biology
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Description
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Comprehensive surveillance systems are the key to provide accurate data for effective modeling. Traditional symptom-based case surveillance has been joined with recent genomic, serologic, and environment surveillance to provide more integrated dis...
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Title
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Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia : implication for malaria diagnosis
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Author
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Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background Rapid diagnostic tests (RDTs) targeting histidine rich protein 2(HRP2) are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the PfHRP3 antigen contributes to the detection of P. falciparum infections in PfH...
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Title
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EchinoDB, an application for comparative transcriptomics of deeply-sampled clades of echinoderms
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Author
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Janies, Daniel, Witter, Zachary, Linchangco, Gregorio V., Jr.
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Date Created
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2016
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Subjects--Topical
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Genomics, Biology
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Description
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Background: One of our goals for the echinoderm tree of life project (http://echinotol.org) is to identify orthologs suitable for phylogenetic analysis from next-generation transcriptome data. The current dataset is the largest assembled for echin...
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Title
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Exploring feasibility of multivariate deep learning models in predicting COVID-19 epidemic
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Author
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Thill, Jean-Claude, Janies, Daniel, Chen, Shi, Paul, Rajib
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Date Created
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2021
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Subjects--Topical
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Deep learning (Machine learning), COVID-19 (Disease)
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Description
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Background: Mathematical models are powerful tools to study COVID-19. However, one fundamental challenge in current modeling approaches is the lack of accurate and comprehensive data. Complex epidemiological systems such as COVID-19 are especially...
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Title
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FLAVi : an enhanced annotator for viral genomes of Flaviviridae
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Author
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Machado, Denis Jacob, Schneider, Adriano, Guirales, Sayal, Janies, Daniel
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Subjects--Topical
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Viruses, Phylogeny
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Description
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Responding to the ongoing and severe public health threat of viruses of the family Flaviviridae, including dengue, hepatitis C, West Nile, yellow fever, and Zika, demands a greater understanding of how these viruses emerge and spread. Updated phyl...
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Title
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Fundamentals of genomic epidemiology, lessons learned from the coronavirus disease 2019 (COVID-19) pandemic, and new directions
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Author
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Machado, Denis Jacob, White, Richard Allen, III, Kofsky, Janice, Janies, Daniel
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Subjects--Topical
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COVID-19 (Disease), Epidemiology
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Description
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The coronavirus disease 2019 (COVID-19) pandemic was one of the significant causes of death worldwide in 2020. The disease is caused by severe acute coronavirus syndrome (SARS) coronavirus 2 (SARS-CoV-2), an RNA virus of the subfamily Orthocoronav...
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Title
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Genetic diversity of Anopheles stephensi in Ethiopia provides insight into patterns of spread
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background: The recent detection of the South Asian malaria vector Anopheles stephensi in the Horn of Africa (HOA) raises concerns about the impact of this mosquito on malaria transmission in the region. Analysis of An. stephensi genetic diversity...
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Title
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Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia : its impact on the performance of malaria rapid diagnostic tests
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Author
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Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
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Date Created
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2021
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background Rapid diagnostic tests (RDT) are commonly used for the diagnosis of malaria caused by Plasmodium falciparum. However, false negative results of RDT caused by genetic variation of P. falciparum histidine-rich protein 2 and 3 genes (pfhrp...
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Title
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Geographical distribution of Anopheles stephensi in eastern Ethiopia
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Author
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Janies, Daniel, Lopez, Karen
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Date Created
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2020
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Subjects--Topical
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Communicable diseases, Malaria
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Description
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Background The recent detection of the South Asian malaria vector Anopheles stephensi in Ethiopia and other regions in the Horn of Africa has raised concerns about its potential impact on malaria transmission. We report here the findings of a surv...