Search results | J. Murrey Atkins Library

Title: A subterminal growth zone at arm tip likely underlies life-long indeterminate growth in brittle stars
Author: Janies, Daniel, Machado, Denis Jacob, Reid, Robert, Kofsky, Janice
Date Created: 2022
Subjects--Topical: Genomics, Biology
Description: Background Echinoderms are a phylum of marine invertebrates with close phylogenetic relationships to chordates. Many members of the phylum Echinodermata are capable of extensive post-traumatic regeneration and life-long indeterminate growth. Diffe...

Title: Active Notch signaling is required for arm regeneration in a brittle star
Author: Janies, Daniel, Machado, Denis Jacob, Reid, Robert
Date Created: 2020
Subjects--Topical: Genomics, Biology
Description: Cell signaling pathways play key roles in coordinating cellular events in development. The Notch signaling pathway is highly conserved across all multicellular animals and is known to coordinate a multitude of diverse cellular events, including pr...

Title: Comparative phylogenetic studies on Schistosoma japonicum and its snail intermediate host Oncomelania hupensis : origins, dispersal and coevolution
Author: Attwood, Stephen W., Ibaraki, Motomu, Saitoh, Yasuhide, Janies, Daniel
Subjects--Topical: Parasites, Coevolution, Public health
Description: Schistosoma japonicum causes major public health problems in China and the Philippines; this parasite, which is transmitted by freshwater snails of the species Oncomelania hupen- sis, causes the disease intestinal schistosomiasis in humans and cat...

Title: Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia : implication for malaria diagnosis
Author: Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
Date Created: 2021
Subjects--Topical: Communicable diseases, Malaria
Description: Background Rapid diagnostic tests (RDTs) targeting histidine rich protein 2(HRP2) are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the PfHRP3 antigen contributes to the detection of P. falciparum infections in PfH...

Title: EchinoDB : an update to the web-based application for genomic and transcriptomic data on echinoderms
Author: Janies, Daniel
Date Created: 2022
Subjects--Topical: Genomics, Biology
Description: Background: Here we release a new version of EchinoDB, EchinoDB v2.0 (https://echinodb.uncc.edu). EchinoDB is a database of genomic and transcriptomic data on echinoderms. The initial database consisted of groups of 749,397 orthologous and paralog...

Title: EchinoDB, an application for comparative transcriptomics of deeply-sampled clades of echinoderms
Author: Janies, Daniel, Witter, Zachary, Linchangco, Gregorio V., Jr.
Date Created: 2016
Subjects--Topical: Genomics, Biology
Description: Background: One of our goals for the echinoderm tree of life project (http://echinotol.org) is to identify orthologs suitable for phylogenetic analysis from next-generation transcriptome data. The current dataset is the largest assembled for echin...

Title: FLAVi : an enhanced annotator for viral genomes of Flaviviridae
Author: Machado, Denis Jacob, Schneider, Adriano, Guirales, Sayal, Janies, Daniel
Subjects--Topical: Viruses, Phylogeny
Description: Responding to the ongoing and severe public health threat of viruses of the family Flaviviridae, including dengue, hepatitis C, West Nile, yellow fever, and Zika, demands a greater understanding of how these viruses emerge and spread. Updated phyl...

Title: Frequent expansion of Plasmodium vivax Duffy Binding Protein in Ethiopia and its epidemiological significance
Author: Janies, Daniel, Lo, Eugenia, Kepple, Daniel
Date Created: 2019
Subjects--Topical: Communicable diseases, Malaria
Description: Plasmodium vivax invasion of human erythrocytes depends on the Duffy Binding Protein (PvDBP) which interacts with the Duffy antigen. PvDBP copy number has been recently shown to vary between P. vivax isolates in Sub-Saharan Africa. However, the ex...

Title: Fundamental evolution of all Orthocoronavirinae including three deadly lineages descendent from Chiroptera-hosted coronaviruses : SARS-CoV, MERS-CoV and SARS-CoV-2
Author: Machado, Denis Jacob, Scott, Rachel, Guirales, Sayal, Janies, Daniel
Subjects--Topical: Coronaviruses, SARS (Disease), MERS (Disease), COVID-19 (Disease)
Description: The severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in humans in 2002. Despite reports showing Chiroptera as the original animal reservoir of SARS-CoV, many argue that Carnivora-hosted viruses are the most likely origin. The emerg...

Title: Fundamentals of genomic epidemiology, lessons learned from the coronavirus disease 2019 (COVID-19) pandemic, and new directions
Author: Machado, Denis Jacob, White, Richard Allen, III, Kofsky, Janice, Janies, Daniel
Subjects--Topical: COVID-19 (Disease), Epidemiology
Description: The coronavirus disease 2019 (COVID-19) pandemic was one of the significant causes of death worldwide in 2020. The disease is caused by severe acute coronavirus syndrome (SARS) coronavirus 2 (SARS-CoV-2), an RNA virus of the subfamily Orthocoronav...

Title: Gene polymorphisms among Plasmodium vivax geographical isolates and the potential as new biomarkers for gametocyte detection
Author: Janies, Daniel, Lo, Eugenia, Ford, Anthony
Date Created: 2022
Subjects--Topical: Genomics, Biology
Description: The unique biological features of Plasmodium vivax not only make it difficult to control but also to eliminate. For the transmission of the malaria parasite from infected human to the vector, gametocytes play a major role. The transmission potenti...

Title: Genetic diversity of Anopheles stephensi in Ethiopia provides insight into patterns of spread
Author: Janies, Daniel, Lopez, Karen
Date Created: 2021
Subjects--Topical: Communicable diseases, Malaria
Description: Background: The recent detection of the South Asian malaria vector Anopheles stephensi in the Horn of Africa (HOA) raises concerns about the impact of this mosquito on malaria transmission in the region. Analysis of An. stephensi genetic diversity...

Title: Genetic variation of Plasmodium falciparum histidine-rich protein 2 and 3 in Assosa zone, Ethiopia : its impact on the performance of malaria rapid diagnostic tests
Author: Janies, Daniel, Blackburn, Kayla, Lopez, Karen, Lo, Eugenia
Date Created: 2021
Subjects--Topical: Communicable diseases, Malaria
Description: Background Rapid diagnostic tests (RDT) are commonly used for the diagnosis of malaria caused by Plasmodium falciparum. However, false negative results of RDT caused by genetic variation of P. falciparum histidine-rich protein 2 and 3 genes (pfhrp...

Title: Geographical distribution of Anopheles stephensi in eastern Ethiopia
Author: Janies, Daniel, Lopez, Karen
Date Created: 2020
Subjects--Topical: Communicable diseases, Malaria
Description: Background The recent detection of the South Asian malaria vector Anopheles stephensi in Ethiopia and other regions in the Horn of Africa has raised concerns about its potential impact on malaria transmission. We report here the findings of a surv...

Title: Insecticide resistance in Anopheles stephensi in Somali Region, eastern Ethiopia
Author: Janies, Daniel, Lopez, Karen
Date Created: 2020
Subjects--Topical: Communicable diseases, Malaria
Description: Background The movement of malaria vectors into new areas is a growing concern in the efforts to control malaria. The recent report of Anopheles stephensi in eastern Ethiopia has raised the necessity to understand the insecticide resistance status...

Title: Modeling Plasmodium falciparum diagnostic test sensitivity using machine learning with histidine-rich protein 2 variants
Author: Ford, Colby, Janies, Daniel, Alemayehu, Gezahegn, Lo, Eugenia, Blackburn, Kayla, Lopez, Karen, Dieng, Cheikh Cambel, Golassa, Lemu
Subjects--Topical: Malaria, Plasmodium falciparum
Description: Malaria, predominantly caused by Plasmodium falciparum, poses one of largest and most durable health threats in the world. Previously, simplistic regression-based models have been created to characterize malaria rapid diagnostic test performance, ...

Title: Phylogeny of echinoderm hemoglobins
Author: Janies, Daniel, Linchangco, Gregorio V., Jr.
Date Created: 2015
Subjects--Topical: Genomics, Biology
Description: Background Recent genomic information has revealed that neuroglobin and cytoglobin are the two principal lineages of vertebrate hemoglobins, with the latter encompassing the familiar myoglobin and alpha-globin/beta-globin tetramer hemoglobin, and ...

Title: Phylotranscriptomic analysis uncovers a wealth of tissue inhibitor of metalloproteinases variants in echinoderms
Author: Janies, Daniel, Clouse, Ronald M., Linchangco, Gregorio V., Jr.
Date Created: 2015
Subjects--Topical: Genomics, Biology
Description: Tissue inhibitors of metalloproteinases (TIMPs) help regulate the extracellular matrix (ECM) in animals, mostly by inhibiting matrix metalloproteinases (MMPs). They are important activators of mutable collagenous tissue (MCT), which have been exte...

Title: Sequence-based identification of Anopheles species in eastern Ethiopia
Author: Janies, Daniel, Lopez, Karen
Date Created: 2019
Subjects--Topical: Communicable diseases, Malaria
Description: Background: The recent finding of a typically non-African Anopheles species in eastern Ethiopia emphasizes the need for detailed species identification and characterization for effective malaria vector surveillance. Molecular approaches increase t...

Title: The first complete mitochondrial genome of the sand dollar Sinaechinocyamus mai (Echinoidea: Clypeasteroida)
Author: Janies, Daniel, Machado, Denis Jacob
Date Created: 2020
Subjects--Topical: Genomics, Biology
Description: Morphologic and molecular data often lead to different hypotheses of phylogenetic relationships. Such incongruence has been found in the echinoderm class Echinoidea. In particular, the phylogenetic status of the order Clypeasteroida is not well re...