Search results | J. Murrey Atkins Library

Title: A comparison of transgenic and wild type soybean seeds : analysis of transcriptome profiles using RNA-Seq
Author: Loraine, Ann, Lambirth, Kevin C., Whaley, Adam M., Piller, Kenneth J.
Date Created: 2015
Subjects--Topical: Gene expression, Biotechnology
Description: Background: Soybean (Glycine max) has been bred for thousands of years to produce seeds rich in protein for human and animal consumption, making them an appealing bioreactor for producing valuable recombinant proteins at high levels. However, the ...

Title: Cytosolic DNA sensors and glial responses to endogenous DNA
Author: Marriott, Ian, Suptela, Alexander J.
Date Created: 2023
Subjects--Topical: Genomics, DNA
Description: Genomic instability is a key driving force for the development and progression of many neurodegenerative diseases and central nervous system (CNS) cancers. The initiation of DNA damage responses is a critical step in maintaining genomic integrity ...

Title: Alternate Reality Games (ARGs) as a lens of participatory learning and exposure to environmental racism in the United States
Author: Alabi, Mora, Fotiushang, Nikol
Date Created: 2023
Subjects--Topical: Alternate reality games, Environmental racism
Description: Contemporary educational models emphasize educators employ tools to increase engagement and collaborative thinking in student learning. Alternate Reality Games (ARGs) have recently been found to have great potential for language immersion and cult...

Title: Submicroscopic infection and G6PD deficiency in malaria patients
Author: Witherspoon, Logan, Witherspoon, Logan, Kepple, Daniel, Lo, Eugenia, Abagero, Beka
Date Created: 2022, 2022, 2022
Subjects--Topical: Malaria, Public health
Description: Plasmodium vivax malaria is a neglected tropical disease, despite being more geographically widespread than any other form of malaria. Glucose-6-phosphate dehydrogenase (G6PD) is a cytosolic enzyme with a vital role for the integrity and functioni...

Title: Genetic architecture of early vigor traits in wild soybean
Author: Song, Bao-Hua, Kofsky, Janice, Zhang, Hengyou
Subjects--Topical: Genetics, Genomics, Soybean
Description: A worldwide food shortage has been projected as a result of the current increase in global population and climate change. In order to provide sufficient food to feed more people, we must develop crops that can produce higher yields. Plant early vi...

Title: Genomic alterations and abnormal expression of APE2 in multiple cancers
Author: Yan, Shan, Jensen, Katherine A., Shi, Xinghua
Subjects--Topical: Cancer--Genetic aspects, DNA repair
Description: Although APE2 plays essential roles in base excision repair and ATR-Chk1 DNA damage response (DDR) pathways, it remains unknown how the APE2 gene is altered in the human genome and whether APE2 is differentially expressed in cancer patients. Here,...

Title: Cell cycle arrest in G2/M phase enhances replication of interferon-sensitive cytoplasmic RNA viruses via inhibition of antiviral gene expression
Author: Grdzelishvili, Valery, Bressy, Christian, Droby, Gaith N., Maldonado, Bryant D., Steuerwald, Nury
Subjects--Topical: Cancer, Viruses
Description: Vesicular stomatitis virus (VSV) (a rhabdovirus) and its variant VSV-ΔM51 are widely used model systems to study mechanisms of virus-host interactions. Here, we investigated how the cell cycle affects replication of these viruses using an array of...

Title: New perspectives on SNARE function in the yeast minimal endomembrane system
Author: Chi, Richard J., Grissom, James H., Segarra, Veronica A.
Subjects--Topical: Endocytosis, Cells
Description: Saccharomyces cerevisiae is one of the best model organisms for the study of endocytic membrane trafficking. While studies in mammalian cells have characterized the temporal and morphological features of the endocytic pathway, studies in budding y...

Title: Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus
Author: Grdzelishvili, Valery, Hastie, Eric Lawrence, Cataldi, Marcela, Moerdyk-Schauwecker, Megan J., Felt, Sebastien A., Steuerwald, Nury
Subjects--Topical: Cancer, Viruses
Description: Vesicular stomatitis virus (VSV) based recombinant viruses (such as VSV-ΔM51) are effective oncolytic viruses (OVs) against a majority of pancreatic ductal adenocarcinoma (PDAC) cell lines. However, some PDAC cell lines are highly resistant to VSV...

Title: Acquired chemoresistance can lead to increased resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus
Author: Grdzelishvili, Valery, Goad, Dakota, Bressy, Christian, Holbrook, Molly
Subjects--Topical: Vesicular stomatitis, Cancer, Viruses
Description: Vesicular stomatitis virus (VSV) is a promising oncolytic virus (OV) against different malignancies, including pancreatic ductal adenocarcinoma (PDAC). Our previous studies have demonstrated that VSV-based OVs are effective against the majority of...

Title: Combining oncolytic virotherapy with p53 tumor suppressor gene therapy
Author: Grdzelishvili, Valery, Bressy, Christian, Hastie, Eric Lawrence
Subjects--Topical: Cancer, Gene therapy
Description: Oncolytic virus (OV) therapy utilizes replication-competent viruses to kill cancer cells, leaving non-malignant cells unharmed. With the first U.S. Food and Drug Administration-approved OV, dozens of clinical trials ongoing, and an abundance of tr...

Title: Creating an online scientific art exhibit formatted for people with a visual impairment
Author: Sorrell, Melanie, Norton, Derek R., McAdams, Jeff, Winterling, Rachael, Dipple, Kathleen
Subjects--Topical: People with visual disabilities, Accessible Web sites for people with disabilities, Academic libraries
Description: An online exhibit accessible by people with a visual impairment was created to accompany a university library’s physical exhibit of microscopic images generated by researchers on campus as “scientific art.” This online exhibit consisted of a Web p...

Title: Low-dose metformin as a monotherapy does not reduce non-small-cell lung cancer tumor burden in mice
Author: Marino, Joseph S., Stott Bond, Nicole L., Dréau, Didier, Marriott, Ian, Bennett, Jeanette M., Turner, Michael J., Arthur, Susan
Subjects--Topical: Lungs--Cancer, Musculoskeletal system
Description: Non-small-cell lung cancer (NSCLC) makes up 80–85% of lung cancer diagnoses. Lung cancer patients undergo surgical procedures, chemotherapy, and/or radiation. Chemotherapy and radiation can induce deleterious systemic side effects, particularly wi...

Title: Modeling Plasmodium falciparum diagnostic test sensitivity using machine learning with histidine-rich protein 2 variants
Author: Ford, Colby, Janies, Daniel, Alemayehu, Gezahegn, Lo, Eugenia, Blackburn, Kayla, Lopez, Karen, Dieng, Cheikh Cambel, Golassa, Lemu
Subjects--Topical: Malaria, Plasmodium falciparum
Description: Malaria, predominantly caused by Plasmodium falciparum, poses one of largest and most durable health threats in the world. Previously, simplistic regression-based models have been created to characterize malaria rapid diagnostic test performance, ...

Title: The immunorecognition, subcellular compartmentalization, and physicochemical properties of nucleic acid nanoparticles can be controlled by composition modification
Author: Johnson, M. Brittany, Halman, Justin, Marriott, Ian, Afonin, Kirill A., Miller, Daniel K., Cooper, Joseph S., Khisamutdinov, Emil F.
Subjects--Topical: Immunology, Nucleic acids, Nanoparticles
Description: Nucleic acid nanoparticles (NANPs) have become powerful new platforms as therapeutic and diagnostic tools due to the innate biological ability of nucleic acids to identify target molecules or silence genes involved in disease pathways. However, th...

Title: The complete mitochondrial genome of the sea urchin, Echinometra sp. EZ
Author: Ketchum, Remi, DeBiasse, Melissa B., Ryan, Joseph F., Burt, John A., Reitzel, Adam M.
Subjects--Topical: Mitochondrial DNA, Sea urchins
Description: The complete mitogenome of Echinometra sp. EZ has been described and fully annotated in this study. Phylogenetic analysis of cytochrome c oxidase subunit I (COI) from six Echinometra species confirms that our sample is E. sp. EZ. The mitogenome is...

Title: Transcriptome profiling of a beach-adapted wild legume for dissecting novel mechanisms of salinity tolerance
Author: Song, Bao-Hua, Zhang, Hengyou, Zuelsdorf, Christine, Penneys, Darin
Subjects--Topical: Plant ecology, Gene expression
Description: Strophostyles helvola is a close relative to common bean (Phaseolus vulgaris) and inhabits both coastal and non-coastal regions in North America. However, the mechanism of saline adaptation in S. helvola remains unclear. A transcriptome profiling ...

Title: APE2 promotes DNA damage response pathway from a single-strand break
Author: Yan, Shan, Lin, Yunfeng, Bai, Liping, Cupello, Steven
Date Created: 2018
Subjects--Topical: Cancer--Research, DNA
Description: As the most common type of DNA damage, DNA single-strand breaks (SSBs) are primarily repaired by the SSB repair mechanism. If not repaired properly or promptly, unrepaired SSBs lead to genome stability and have been implicated in cancer and neurod...

Title: Intracellular lipid homeostasis and trafficking in autophagy
Author: Chi, Richard J., Goyal, Shreya, Robinson, Meaghan, Segarra, Veronica A.
Subjects--Topical: Lipids, Cells--Growth
Description: In eukaryotes, lipids are not only an important constituent of the plasma membrane but are also used to generate specialized membrane-bound organelles, including temporary compartments with critical functions. As such, lipids play a key role in in...

Title: Symbiotic life of echinoderm larvae
Author: Carrier, Tyler J., Reitzel, Adam M.
Date Created: 2020
Subjects--Topical: Symbiosis, Life sciences, Marine biology
Description: Echinoderms larvae have served as a fundamental system for understanding development and life history evolution over much of the last century. In the last few decades, our understanding of echinoderm larvae has expanded to the microbiota that they...