Search results | J. Murrey Atkins Library

Title: Development of a Methanotrophic Alternative Daily Cover to Reduce Early Landfill Methane Emissions
Author: Adams, Bryn
Date Created: 2009
Subjects--Topical: Microbiology, Environmental engineering, Environmental sciences
Description: Final covers, especially when supplemented with gas collection, are highly engineered systems to prevent landfill methane release into the atmosphere. However, some methane production begins even before open cells are covered and often well before...

Title: Apoptotic T-cell derived microparticles containing sonic hedgehog modulate endothelial cell functions in inflammation via rho kinase pathway
Author: Attal, Neha
Date Created: 2019
Subjects--Topical: Biology
Description: Impaired vascular regulation as a result of endothelial dysfunction is a major determinant of sepsis-associated liver failure. We have previously shown that inhibition of one signaling molecule rho-kinase (ROCK) predominantly restores endothelial ...

Title: EFFECT OF CADMIUM AND SEASONALITY ON CRITICAL TEMPERATURES OF AEROBIC METABOLISM IN EASTERN OYSTERS, Crassostrea virginica Gmelin 1791
Author: Bagwe, Rita
Date Created: 2012
Subjects--Topical: Biology
Description: Cadmium (Cd) and elevated temperatures are common stressors in estuarine and coastal environments affecting intertidal mollusks such as oysters. Cd and elevated temperature can raise the metabolic demands of oysters due to the increase cost of det...

Title: Topoisomerase II Inhibitors Induce an Illegitimate Genome Rearrangement Common in Infant Leukemia
Author: Bariar, Bhawana
Date Created: 2013
Subjects--Topical: Molecular biology
Description: Infant acute leukemias account for ~30% of all malignancy seen in childhood across the Western world. They are aggressive and characterized by rapid onset shortly after birth. The majority of these have rearrangements involving the MLL (mixed line...

Title: IDENTIFICATION OF EPITHELIAL OVARIAN TUMOR SPECIFIC APTAMERS THAT BIND AND INTERNALIZE INTO TARGET CELLS
Author: Benedetto, Gregory
Date Created: 2015
Subjects--Topical: Chemistry, Biology
Description: New clinical tools that aid in the early diagnosis of ovarian malignancies will significantly help reduce mortality and improve current long-term survival rates. The objective of the work presented here was to identify ovarian tumor specific singl...

Title: THE DEVELOPMENT OF NOVEL THERAPEUTICS IN PANCREATIC AND BREAST CANCERS: POTENTIAL ROLE OF MUC1
Author: Besmer, Dahlia
Date Created: 2013
Subjects--Topical: Biology
Description: Pancreatic ductal adenocarcinoma (PDA) is the 4th leading cause of cancer-related deaths in the US, and breast cancer (BC) contributes to ~40,000 deaths annually. The development of novel therapeutic agents for improving patient outcome is of para...

Title: Characterizing a New Regulator of the ATR Signaling Pathway
Author: Biller, Megan
Date Created: 2022
Subjects--Topical: Molecular biology, Biology
Description: Cellular responses to DNA damage and replication stress are coordinated by an intricate network of repair pathways known as the DNA damage response (DDR). Central to the DDR is the essential kinase ataxia telangiectasia mutated and Rad3-related (A...

Title: The Role of Metformin on Non-Small Cell Lung Cancer Progression and Skeletal Muscle Health.
Author: Bond, Nicole
Date Created: 2021
Subjects--Topical: Molecular biology, Kinesiology
Description: Lung cancer is the second most common cancer and maintains a relatively small survival rate (~20%). Non-Small Cell Lung Cancer (NSCLC) makes up 80-85% of all lung cancer diagnoses. Lung cancer patients routinely undergo surgical procedures, chemot...

Title: Abrogating the oncogenic signaling associated with tumor MUC1 in Pancreatic Ductal Adenocarcinoma
Author: Bose, Mukulika
Date Created: 2022
Subjects--Topical: Molecular biology, Biochemistry, Oncology
Description: Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal human cancers. The incidence rate of PDA nearly matches its mortality rate and the best treatment till date is surgical resection for which only 25\% are eligible. Tumor recurrence a...

Title: The role of the sex steroids in regulation of physical activity levels in mice
Author: Bowen, Robert
Date Created: 2010
Subjects--Topical: Kinesiology, Physiology
Description: Low physical activity (PA) levels are associated with many chronic diseases and place a massive burden on the health care system. The extrinsic environment has been suggested to regulate activity levels, but an increasing prevalence of physical in...

Title: The Role of the Cell Cycle in Karlodinium veneficum Toxicity: Tools and Predictions From the Laboratory
Author: Broemsen, Erik
Date Created: 2023
Subjects--Topical: Biology, Marine biology, Microbiology
Description: The toxic dinoflagellate Karlodinium veneficum forms blooms in estuaries worldwide. These blooms are often associated with severe fish mortalities that are largely caused by production of karlotoxins. The toxicity of these blooms can vary between ...

Title: CORTICAL ACTIVITY OF THE SENSORIMOTOR SYSTEM IN PARTICIPANTS WITH CHRONIC ANKLE INSTABILITY
Author: Burcal, Christopher
Date Created: 2017
Subjects--Topical: Biology, Kinesiology, Neurosciences
Description: Patients with chronic ankle instability (CAI) exhibit a wide variety of sensorimotor deficits. These include impairments in feed-forward sensorimotor control (i.e. motor planning) as well as feed-back sensorimotor control, which pertains to refini...

Title: Detrimental brain inflammation and the role of the interleukin 10 family members
Author: Burmeister, Amanda
Date Created: 2019
Subjects--Topical: Biology
Description: Resident brain cells recognize pathogens and can initiate and/or regulate inflammation. Indeed, we have shown that stimulated glial cells rapidly produce inflammatory mediators, followed by the late production of anti-inflammatory cytokines such a...

Title: SYMBIOSIS ACROSS DIET-INDUCED PHENOTYPES OF LARVAL SEA URCHINS
Author: Carrier, Tyler
Date Created: 2020
Subjects--Topical: Microbiology, Ecology, Aquatic sciences
Description: Larval sea urchins have served as a fundamental system for understanding development, phenotypic plasticity, and life-history evolution over much of the last century. In the recent decade, this understanding has begun to extend to the microbiota a...

Title: ASSESSING COMPARATIVE FUNCTIONS FOR THE BZIP TRANSCRIPTION FACTOR NFE2 IN NEMATOSTELLA VECTENSIS
Author: Clegg, Devin
Date Created: 2020
Subjects--Topical: Biology
Description: The bZIP gene superfamily is a family of transcription factors that have gone through multiple duplication events within bilaterians, specifically in vertebrates. This has led to multiple paralogs in each bZIP family while early diverging phyla ha...

Title: INVESTIGATING THE ROLE OF NEWLY DESCRIBED CYTOSOLIC PATTERN RECOGNITION RECEPTORS IN PROTECTIVE HOST RESPONSES TO NEUROTROPIC VIRUSES
Author: Crill, Emma
Date Created: 2014
Subjects--Topical: Immunology, Virology
Description: The importance of the effector functions performed by glial cells, the resident cells of the CNS possessing immune functions, in abrogating potentially fatal neurotropic viral infections have only recently begun to gain appreciation. These effecto...

Title: THE ROLE OF XRCC1 AND POLYMERASE BETA IN GENOME INTEGRITY IN XENOPUS EGG EXTRACTS
Author: Cupello, Steven
Date Created: 2019
Subjects--Topical: Molecular biology, Biology, Cytology
Description: Cells of organisms are constantly exposed to genomic insults such as oxidative stress from endogenous sources or environmental agents. Oxidative stress induces oxidative DNA damage such as apurinic/apyrimidinic (AP) sites, single-strand breaks (SS...

Title: RECIPROCAL REGULATION OF MYC AND MICRORNA MIR-308 DURING DROSOPHILA EMBRYOGENESIS
Author: Daneshvar, Kaveh
Date Created: 2012
Subjects--Topical: Molecular biology, Biology, Genetics
Description: Myc is a conserved transcription factor with a role in the regulation of genes that are involved in growth and development. The abundance of Myc protein in the cells must be exquisitely controlled to avoid growth abnormalities caused by too much o...

Title: Insights Into Plasmodium Genetic Changes Related To Malaria Interventions
Author: Dieng, Cheikh
Date Created: 2023
Subjects--Topical: Biology, Parasitology, Genetics
Description: Over 80% of all malaria deaths occur in children under 5 years of age. Malaria controlstrategies have been progressively shifted to specific populations and/or areas to maximize effectiveness. Malaria is a significant public health problem in Ghan...

Title: The Impact of Geographic Location on Larval Mortality and Analysis of Gene Expression in Nematostella vectensis Exposed to Acute and Chronic Thermal Stress
Author: Estvander, Sarah
Date Created: 2023
Subjects--Topical: Biology, Genetics
Description: Environmental temperature plays a critical role in the survival and geographic distribution of most organisms, as it can directly influence the rate of all biochemical and physiological reactions. Recent climate models show that seasonal variation...