Search results | J. Murrey Atkins Library

Title: ROLE OF THE NOVEL DNA SENSORS cGAS, IFI16, AND ZBP1, DURING VIRAL INFECTIONS IN GLIA
Author: Jeffries, Austin
Date Created: 2020
Subjects--Topical: Immunology, Virology, Neurosciences
Description: Viral central nervous system (CNS) infections can lead to life threatening encephalitis and long-term neurological deficits in survivors. Resident CNS cell types, such as astrocytes and microglia, are known to produce key inflammatory and antivira...

Title: Examining the Contribution of the DNA Damage Response to Sepsis Survivor Myelosuppression
Author: Huff, Laura
Date Created: 2020
Subjects--Topical: Immunology, Biology, Pathology
Description: A large portion of patients who survive sepsis, a life-threatening hyperinflammatory response to infection resulting in organ dysfunction, experience a higher risk of mortality than non-septic patients. Innate immune cells of sepsis survivors exhi...

Title: Newly described cytosolic pattern recognition receptors mediate inflammatory glial responses to neurotropic viruses
Author: Furr, Samantha
Date Created: 2012
Subjects--Topical: Immunology, Biology
Description: The rapid onset of potentially lethal neuroinflammation is a defining feature of viral encephalitis. Glial cells are ideally positioned to respond to invading pathogens of the central nervous system (CNS) and produce key inflammatory mediators fol...

Title: THE ROLE OF MUC1 IN REGULATION AND PROGRESSION OF CANCER
Author: Sahraeimanouchehrabadi, Mahnaz
Date Created: 2011
Subjects--Topical: Immunology, Biology, Oncology
Description: MUC1 is a heavily glycosylated transmembrane glycoprotein which is overexpressed and aberrantly glycosylated in most human carcinomas. MUC1 contains a large tandem repeat, a short transmembrane, and a small cytoplasmic tail. Both tandem repeat and...

Title: Study of the Intracellular Protein Tau and its Relationship with Kunjin Virus and Neurodegenerative Diseases
Author: Lotz, Sarah
Date Created: 2022
Subjects--Topical: Neurosciences, Immunology, Virology
Description: Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, comprise a family of disorders characterized by progressive loss of nervous system function. Neuroinflammation is increasingly recogni...

Title: Role of the DNA Sensors cGAS and ZBP1 in DNA Damage and Viral Infection
Author: Suptela, Alexander
Date Created: 2023
Subjects--Topical: Immunology, Molecular biology, Neurosciences
Description: Genomic instability is a key driving force for the development and progression of many neurodegenerative diseases and central nervous system (CNS) cancers. The initiation of DNA damage responses (DDRs) is a critical step in maintaining genomic int...

Title: INVESTIGATING THE ROLE OF NEWLY DESCRIBED CYTOSOLIC PATTERN RECOGNITION RECEPTORS IN PROTECTIVE HOST RESPONSES TO NEUROTROPIC VIRUSES
Author: Crill, Emma
Date Created: 2014
Subjects--Topical: Immunology, Virology
Description: The importance of the effector functions performed by glial cells, the resident cells of the CNS possessing immune functions, in abrogating potentially fatal neurotropic viral infections have only recently begun to gain appreciation. These effecto...

Title: Inflammation, NLRP3 Inflammasomes, Macrophages and Breast Cancer Progression
Author: Holtzman , Katherine
Date Created: 2021
Subjects--Topical: Biology, Immunology, Oncology
Description: One in 8 women will be diagnosed with breast cancer in their lifetime and while breast cancer mortality has declined since the 1980s, it remains the 2nd leading cause of cancer-related deaths among women. Standard of care is determined by anatomic...