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Regulation of Myc and its Localization to Histone Locus Body in Drosophila
Title
Regulation of Myc and its Localization to Histone Locus Body in Drosophila
Author
Khan, Abid
Date Created
2012
Subjects--Topical
Molecular biology, Biology, Developmental biology
Description
Myc is a transcriptional factor required for normal growth and development in vertebrates and invertebrates alike. Loss of function mutations in Myc can cause embryonic lethality in mammals and larval death in flies whereas an increase in its acti...
Cell Type-Specific Double Strand Break Repair: An Inter-Chromosomal Homologous Recombination Study Using the Rainbow Mouse Model
Title
Cell Type-Specific Double Strand Break Repair: An Inter-Chromosomal Homologous Recombination Study Using the Rainbow Mouse Model
Author
Lalwani, Kiran
Date Created
2023
Subjects--Topical
Molecular biology, Cytology, Developmental biology
Description
Faithful repair of DNA lesions is central to maintaining genomic integrity. Illegitimate repair of chromosomal DNA damage, especially double-strand breaks (DSBs), can lead to mutations and genome rearrangements. Homologous recombination (HR) is a ...