Search results
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Title
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The Local Dynamics of Basement Membrane Breaching During Cancer Cell Invasion
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Author
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Nazari, Shayan
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Date Created
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2022
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Subjects--Topical
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Biology
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Description
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Solid tumor metastasis is the leading cause of cancer-related mortality. Cancer invasion through the confining basement membrane (BM) is the initial step in tumor dissemination and metastasis, and it represents a key diagnostic feature of cancer. ...
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Title
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Fibroblast-driven Fibrosis and Inflammation in Breast Cancer Progression
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Author
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Samuels, Courtney
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Date Created
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2022
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Subjects--Topical
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Biology
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Description
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Breast cancer progression is promoted by both local inflammation and fibrosis. Indeed,accumulation of fibrous collagen is an independent prognosis marker of breast cancer. However, the mechanisms underlying the interplay between fibroblasts, infla...
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Title
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Genetic Structure and Gene Expression Profile of Plasmodium vivax in East Africa
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Author
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Kepple, Daniel
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Date Created
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2022
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Subjects--Topical
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Biology, Molecular biology, Cytology
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Description
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Plasmodium vivax malaria is a neglected tropical disease, despite being more geographically widespread than any other form of malaria. P. vivax was previously thought to be rare or absent in Africa because people of African descent often lack the ...
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Title
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Characterizing a New Regulator of the ATR Signaling Pathway
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Author
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Biller, Megan
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Date Created
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2022
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Subjects--Topical
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Molecular biology, Biology
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Description
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Cellular responses to DNA damage and replication stress are coordinated by an intricate network of repair pathways known as the DNA damage response (DDR). Central to the DDR is the essential kinase ataxia telangiectasia mutated and Rad3-related (A...