Search results
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Title
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A STRUCTURAL AND FUNCTIONAL ANALYSIS OF NEMATOSTELLA VECTENSIS MAJOR INTRINSIC PROTEINS
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Author
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Taylor, Jonathon
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Date Created
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2020
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Subjects--Topical
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Biology, Cytology, Evolutionary developmental biology
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Description
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There is currently a major gap in understanding the physiological processes of tissue grade animals from early diverging phyla, particularly within the context of the molecular mechanisms in response to osmotic variation. A key protein family esse...
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Title
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CO-CHAPERONE REGULATION OF THE RIBONUCLOETIDE REDUCTASE COMPLEX
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Author
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Knighton, Laura
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Date Created
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2020
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Subjects--Topical
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Biology, Biochemistry
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Description
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The molecular chaperone Hsp70 folds a significant proportion of the proteome and is responsible for the activity and stability of many disease-related proteins, including those in cancer. Substantial effort has been devoted to developing a range o...
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Title
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Oral Microbiome Signature for Hematological Cancer
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Author
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Langdon, Holden
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Date Created
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2020
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Subjects--Topical
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Biology
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Description
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BackgroundThe endogenous microbiome of healthy individuals in the oral cavity is diverse, representing over 700 different bacterial species. Some of these species may become opportunistic if certain elements in the microenvironment and host-respon...
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Title
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REGULATION OF APE1 BY NEIL3 ZINC FINGER-GRF REPEAT ON SINGLE-STRANDED DNA
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Author
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Ha, Anh
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Date Created
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2020
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Subjects--Topical
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Molecular biology, Cytology
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Description
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Base excision repair (BER) is a critical pathway in repairing single base lesions caused by oxidation, deamination, and alkylation. NEIL3 is a DNA glycosylase which functions in initiating BER pathway by recognizing and removing damaged bases. Alt...
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Title
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ROLE OF THE NOVEL DNA SENSORS cGAS, IFI16, AND ZBP1, DURING VIRAL INFECTIONS IN GLIA
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Author
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Jeffries, Austin
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Date Created
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2020
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Subjects--Topical
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Immunology, Virology, Neurosciences
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Description
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Viral central nervous system (CNS) infections can lead to life threatening encephalitis and long-term neurological deficits in survivors. Resident CNS cell types, such as astrocytes and microglia, are known to produce key inflammatory and antivira...
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Title
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SYMBIOSIS ACROSS DIET-INDUCED PHENOTYPES OF LARVAL SEA URCHINS
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Author
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Carrier, Tyler
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Date Created
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2020
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Subjects--Topical
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Microbiology, Ecology, Aquatic sciences
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Description
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Larval sea urchins have served as a fundamental system for understanding development, phenotypic plasticity, and life-history evolution over much of the last century. In the recent decade, this understanding has begun to extend to the microbiota a...