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Title: Abrogating the oncogenic signaling associated with tumor MUC1 in Pancreatic Ductal Adenocarcinoma
Author: Bose, Mukulika
Date Created: 2022
Subjects--Topical: Molecular biology, Biochemistry, Oncology
Description: Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal human cancers. The incidence rate of PDA nearly matches its mortality rate and the best treatment till date is surgical resection for which only 25\% are eligible. Tumor recurrence a...

Title: MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Author: Grover, Priyanka
Date Created: 2019
Subjects--Topical: Biology
Description: In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...

Title: Understanding The Role of Pancreatic Ductal Adenocarcinoma Chemoresistance and Intertumoral Heterogeneity on Vesicular Stomatitis Virus-based Oncolytic Therapy
Author: Goad, Dakota
Date Created: 2023
Subjects--Topical: Biology, Virology, Biomedical engineering
Description: Viruses are obligate intracellular parasites that are now being increasingly harnessed as therapeutics for human diseases. Investigating different cellular factors and processes that affect viral infection allows us to improve the efficacy of viru...