There is growing appreciation that the resident glial cells of the CNS, in particular microglia and astrocytes, are important participants in the generation of inflammation during brain infection. However, the mechanisms by which these cell types ...
The rapid onset of potentially lethal neuroinflammation is a defining feature of viral encephalitis. Glial cells are ideally positioned to respond to invading pathogens of the central nervous system (CNS) and produce key inflammatory mediators fol...