Search results
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Title
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ROLE OF THE NOVEL DNA SENSORS cGAS, IFI16, AND ZBP1, DURING VIRAL INFECTIONS IN GLIA
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Author
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Jeffries, Austin
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Date Created
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2020
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Subjects--Topical
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Immunology, Virology, Neurosciences
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Description
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Viral central nervous system (CNS) infections can lead to life threatening encephalitis and long-term neurological deficits in survivors. Resident CNS cell types, such as astrocytes and microglia, are known to produce key inflammatory and antivira...
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Title
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THE ROLE OF MUC1 IN REGULATION AND PROGRESSION OF CANCER
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Author
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Sahraeimanouchehrabadi, Mahnaz
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Date Created
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2011
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Subjects--Topical
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Immunology, Biology, Oncology
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Description
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MUC1 is a heavily glycosylated transmembrane glycoprotein which is overexpressed and aberrantly glycosylated in most human carcinomas. MUC1 contains a large tandem repeat, a short transmembrane, and a small cytoplasmic tail. Both tandem repeat and...
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Title
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Role of the DNA Sensors cGAS and ZBP1 in DNA Damage and Viral Infection
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Author
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Suptela, Alexander
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Date Created
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2023
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Subjects--Topical
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Immunology, Molecular biology, Neurosciences
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Description
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Genomic instability is a key driving force for the development and progression of many neurodegenerative diseases and central nervous system (CNS) cancers. The initiation of DNA damage responses (DDRs) is a critical step in maintaining genomic int...
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Title
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Inflammation, NLRP3 Inflammasomes, Macrophages and Breast Cancer Progression
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Author
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Holtzman , Katherine
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Date Created
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2021
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Subjects--Topical
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Biology, Immunology, Oncology
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Description
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One in 8 women will be diagnosed with breast cancer in their lifetime and while breast cancer mortality has declined since the 1980s, it remains the 2nd leading cause of cancer-related deaths among women. Standard of care is determined by anatomic...
