Search results
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Title
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A NOVEL ANTIBODY FOR THE DETECTION AND TREATMENT OF PANCREATIC DUCTAL ADENOCARCINOMA
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Author
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Wu, Shuta
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Date Created
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2017
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Subjects--Topical
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Biology, Oncology
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Description
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Pancreatic ductal adenocarcinoma (PDA) remains the most aggressive cancer with a 5-year survival rate below 10%. Two of the major contributors to this dismal prognosis are late-stage diagnosis and limited treatment options. Common symptoms of PDA ...
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Title
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EXPERIMENTAL EVOLUTION OF ONCOLYTIC VESICULAR STOMATITIS VIRUSES IN CANCER CELLS
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Author
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Seegers, Sara
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Date Created
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2019
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Subjects--Topical
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Molecular biology, Virology, Biology
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Description
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Vesicular stomatitis virus (VSV) based oncolytic viruses are promising agents against various cancers. We have shown that pancreatic ductal adenocarcinoma (PDAC) cell lines exhibit great diversity in susceptibility and permissibility to VSV. Here,...
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Title
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HOST FACTORS CONTROLLING VIRUS INFECTION: IMPLICATIONS FOR ANTIVIRALS AND VIROTHERAPY
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Author
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Shah, Nirav
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Date Created
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2013
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Subjects--Topical
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Virology, Oncology
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Description
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Viruses are obligate intracellular parasites rely heavily on host components and pathways for their replication. Studying different cellular factors affecting viral infection can enable us to identify novel drug targets, improve current antiviral ...
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Title
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MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
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Author
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Grover, Priyanka
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Date Created
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2019
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Subjects--Topical
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Biology
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Description
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In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...