Search results | J. Murrey Atkins Library

Title: Functionally-interdependent shape-switching nanoparticles with controllable properties
Author: Halman, Justin, Khisamutdinov, Emil F., Afonin, Kirill A., Satterwhite, Emily, Roark, Brandon, Chandler, Morgan, Ivanina, Anna, Viard, Mathias, Bindewald, Eckart, Kasprzak, Wojciech K., Panigaj, Martin, Bui, My N., Lu, Jacob S., Miller, Johann, Shapiro, Bruce A., Dobrovolskaia, Marina A.
Subjects--Topical: Nucleic acids, Nanotechnology
Description: We introduce a new concept that utilizes cognate nucleic acid nanoparticles which are fully complementary and functionally-interdependent to each other. In the described approach, the physical interaction between sets of designed nanoparticles ini...

Title: Expanding structural space for immunomodulatory nucleic acid nanoparticles (NANPs) via spatial arrangement of their therapeutic moieties
Author: Afonin, Kirill A., Chandler, Morgan, Rolband, Lewis
Date Created: 2022
Subjects--Topical: Nucleic acids, Chemistry
Description: Different therapeutic nucleic acids (TNAs) can be unified in a single structure by their elongation with short oligonucleotides designed to self-assemble into nucleic acid nanoparticles (NANPs). With this approach, therapeutic cocktails with preci...

Title: Smart-responsive nucleic acid nanoparticles (NANPs) with the potential to modulate immune behavior
Author: Afonin, Kirill A., Chandler, Morgan
Date Created: 2019
Subjects--Topical: Nucleic acids, Chemistry
Description: Nucleic acids are programmable and biocompatible polymers that have beneficial uses in nanotechnology with broad applications in biosensing and therapeutics. In some cases, however, the development of the latter has been impeded by the unknown imm...

Title: Broccoli fluorets : split aptamers as a user-friendly fluorescent toolkit for dynamic RNA nanotechnology
Author: Afonin, Kirill A., Chandler, Morgan, Halman, Justin
Date Created: 2018
Subjects--Topical: Nucleic acids, Chemistry
Description: RNA aptamers selected to bind fluorophores and activate their fluorescence offer a simple and modular way to visualize native RNAs in cells. Split aptamers which are inactive until the halves are brought within close proximity can become useful fo...

Title: Artificial immune cell, AI-cell, a new tool to predict interferon production by peripheral blood monocytes in response to nucleic acid nanoparticles
Author: Afonin, Kirill A., Chandler, Morgan, Halman, Justin
Date Created: 2022
Subjects--Topical: Nucleic acids, Chemistry
Description: Nucleic acid nanoparticles, or NANPs, rationally designed to communicate with the human immune system, can offer innovative therapeutic strategies to overcome the limitations of traditional nucleic acid therapies. Each set of NANPs is unique in th...

Title: Functionally-interdependent shape-switching nanoparticles with controllable properties
Author: Afonin, Kirill A., Halman, Justin, Chandler, Morgan
Date Created: 2017
Subjects--Topical: Nucleic acids, Chemistry
Description: We introduce a new concept that utilizes cognate nucleic acid nanoparticles which are fully complementary and functionally-interdependent to each other. In the described approach, the physical interaction between sets of designed nanoparticles ini...