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Development of Structural Informatics Method For Binding Peptides
Title
Development of Structural Informatics Method For Binding Peptides
Author
Patterson, John
Date Created
2023
Subjects--Topical
Bioinformatics
Description
In the continuous pursuit of advanced therapeutics, the field of bioinformatics hasinnovated tools that allow unprecedented control over the proteome, profoundly shaping our understanding and manipulation of biological domains. Computational appro...
Molecular function recognition by supervised projection pursuit machine learning
Title
Molecular function recognition by supervised projection pursuit machine learning
Author
Jacobs, Donald J., Grear, Tyler, Avery, Chris, Patterson, John
Date Created
2021
Subjects--Topical
Molecular biology, Pharmaceutical chemistry
Description
Identifying mechanisms that control molecular function is a significant challenge in pharmaceutical science and molecular engineering. Here, we present a novel projection pursuit recurrent neural network to identify functional mechanisms in the co...
SYNTHESIS AND REACTIVITY OF HETEROCYCLIC THIONE AND SELONE LIGANDS WITH A SATURATED BACKBONE
Title
SYNTHESIS AND REACTIVITY OF HETEROCYCLIC THIONE AND SELONE LIGANDS WITH A SATURATED BACKBONE
Author
Patterson, John
Date Created
2017
Subjects--Topical
Chemistry
Description
ABSTRACTJOHN R. PATTERSON Synthesis and Reactivity of Heterocyclic Thione and Selone Ligands with a Saturated Backbone (Under the direction of DR. DANIEL RABINOVICH) The field of coordination chemistry is so pervasive that it finds use in nearly e...