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Toll-like receptor-mediated recognition of nucleic acid nanoparticles (NANPs) in human primary blood cells
Title
Toll-like receptor-mediated recognition of nucleic acid nanoparticles (NANPs) in human primary blood cells
Author
Afonin, Kirill A., Truong, Nguyen, Halman, Justin
Date Created
2019
Subjects--Topical
Nucleic acids, Chemistry
Description
Infusion reactions (IRs) create a translational hurdle for many novel therapeutics, including those utilizing nanotechnology. Nucleic acid nanoparticles (NANPs) are a novel class of therapeutics prepared by rational design of relatively short olig...