Search results | J. Murrey Atkins Library

Title: Biomotors, viral assembly, and RNA nanobiotechnology : current achievements and future directions
Author: Robland, Lewis, Beasock, Damian, Afonin, Kirill A., Schlick, Tamar
Date Created: 2022
Subjects--Topical: Viruses, Nanotechnology
Description: The International Society of RNA Nanotechnology and Nanomedicine (ISRNN) serves to further the development of a wide variety of functional nucleic acids and other related nanotechnology platforms. To aid in the dissemination of the most recent adv...

Title: Biomotors, viral assembly, and rna nanobiotechnology: current achievements and future directions
Author: Afonin, Kirill A., Rolband, Lewis
Date Created: 2022
Subjects--Topical: Nucleic acids, Chemistry
Description: The International Society of RNA Nanotechnology and Nanomedicine (ISRNN) serves to further the development of a wide variety of functional nucleic acids and other related nanotechnology platforms. To aid in the dissemination of the most recent adv...

Title: Break to build : isothermal assembly of nucleic acid nanoparticles (NANPs) via enzymatic degradation
Author: Beasock, Damian, Ha, Anh, Halman, Justin, Afonin, Kirill A.
Date Created: 2023
Subjects--Topical: Genetics, Peptides
Description: The intrinsic properties of RNA and DNA biopolymers emphasized by engineered nucleic acid nanoparticles (NANPs) offer accelerated development of next-generation therapies. The rational design of NANPs facilitates programmable architectures intende...

Title: Change in lipofectamine carrier as a tool to fine-tune immunostimulation of nucleic acid nanoparticles
Author: Afonin, Kirill A., Newton, Hannah S., Xu, Jie
Date Created: 2023
Subjects--Topical: Nucleic acids, Chemistry
Description: Nucleic acid nanoparticles (NANPs) require a carrier to allow for their intracellular delivery to immune cells. Cytokine production, specifically type I and III interferons, allows for reliable monitoring of the carrier effect on NANP immunostimul...

Title: Characterization of cationic bolaamphiphile vesicles for sirna delivery into tumors and brain
Author: Afonin, Kirill A., Kim, Taejin, Gupta, Kshitij
Date Created: 2020
Subjects--Topical: Nucleic acids, Chemistry
Description: Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). Howeve...

Title: Demonstrating the synthesis and antibacterial properties of nanostructured silver
Author: Rolband, Lewis, Godakhindi, Varsha, Vivero-Escoto, Juan L., Afonin, Kirill A.
Date Created: 2023
Subjects--Topical: Antibacterial agents, Silver
Description: Investigating and understanding novel antibacterial agents is a necessary task as there is a constant increase in the number of multidrug-resistant bacterial species. The use of nanotechnology to combat drug-resistant bacteria is an important rese...

Title: Editorial for the special issue on nucleic acid architectures for therapeutics, diagnostics, devices and materials
Author: Afonin, Kirill A., Halman, Justin
Date Created: 2019
Subjects--Topical: Nucleic acids, Chemistry

Title: Exosome mediated delivery of functional nucleic acid nanoparticles (NANPs)
Author: Afonin, Kirill A., Ke, Weina
Date Created: 2020
Subjects--Topical: Nucleic acids, Chemistry
Description: RNAi-based technologies have shown biomedical potential; however, safe and efficient delivery of RNA remains a barrier for their broader clinical applications. Nucleic acid nanoparticles (NANPs) programmed to self-assemble and organize multiple th...

Title: First step towards larger DNA-based assemblies of fluorescent silver nanoclusters: template design and detailed characterization of optical properties
Author: Afonin, Kirill A., Shevchenko, Oleg
Date Created: 2019
Subjects--Topical: Nucleic acids, Chemistry
Description: Besides being a passive carrier of genetic information, DNA can also serve as an architecture template for the synthesis of novel fluorescent nanomaterials that are arranged in a highly organized network of functional entities such as fluorescent ...

Title: Retinoic acid inducible gene-I mediated detection of bacterial nucleic acids in human microglial cells
Author: Afonin, Kirill A., Marriott, Ian, Halman, Justin
Date Created: 2020
Subjects--Topical: Nucleic acids, Chemistry
Description: Background Bacterial meningitis and meningoencephalitis are associated with devastating neuroinflammation. We and others have demonstrated the importance of glial cells in the initiation of immune responses to pathogens invading the central nervou...

Title: Special issue nanotechnology to overcome the world's most critical health issues: liposomes and beyond-a themed issue dedicated to Professor Yechezkel Barenholz
Author: Afonin, Kirill A., Dobrovolskaia, Marina
Date Created: 2023
Subjects--Topical: Nucleic acids, Chemistry

Title: Structure and composition define immunorecognition of nucleic acid nanoparticles
Author: Afonin, Kirill A.
Date Created: 2022, 2022, 2022
Subjects--Topical: Immune system, Interferon, Nucleic acids

Title: The immunorecognition, subcellular compartmentalization, and physicochemical properties of nucleic acid nanoparticles can be controlled by composition modification
Author: Johnson, M. Brittany, Halman, Justin, Marriott, Ian, Afonin, Kirill A., Miller, Daniel K., Cooper, Joseph S., Khisamutdinov, Emil F.
Subjects--Topical: Immunology, Nucleic acids, Nanoparticles
Description: Nucleic acid nanoparticles (NANPs) have become powerful new platforms as therapeutic and diagnostic tools due to the innate biological ability of nucleic acids to identify target molecules or silence genes involved in disease pathways. However, th...

Title: The immunorecognition, subcellular compartmentalization, and physicochemical properties of nucleic acid nanoparticles can be controlled by composition modification
Author: Afonin, Kirill A., Marriott, Ian, Halman, Justin
Date Created: 2020
Subjects--Topical: Nucleic acids, Chemistry
Description: Nucleic acid nanoparticles (NANPs) have become powerful new platforms as therapeutic and diagnostic tools due to the innate biological ability of nucleic acids to identify target molecules or silence genes involved in disease pathways. However, th...

Title: The recognition of and reactions to nucleic acid nanoparticles by human immune cells
Author: Afonin, Kirill A., Bila, Dominika, Panigaj, Martin
Date Created: 2021
Subjects--Topical: Nucleic acids, Chemistry
Description: The relatively straightforward methods of designing and assembling various functional nucleic acids into nanoparticles offer advantages for applications in diverse diagnostic and therapeutic approaches. However, due to the novelty of this approach...

Title: Therapeutic immunomodulation by rationally designed nucleic acids and nucleic acid nanoparticles
Author: Afonin, Kirill A., Marriott, Ian, Panigaj, Martin
Date Created: 2023
Subjects--Topical: Nucleic acids, Chemistry
Description: The immune system has evolved to defend organisms against exogenous threats such as viruses, bacteria, fungi, and parasites by distinguishing between self and non-self. In addition, it guards us against other diseases, such as cancer, by detecting...

Title: Toll-like receptor-mediated recognition of nucleic acid nanoparticles (NANPs) in human primary blood cells
Author: Afonin, Kirill A., Truong, Nguyen, Halman, Justin
Date Created: 2019
Subjects--Topical: Nucleic acids, Chemistry
Description: Infusion reactions (IRs) create a translational hurdle for many novel therapeutics, including those utilizing nanotechnology. Nucleic acid nanoparticles (NANPs) are a novel class of therapeutics prepared by rational design of relatively short olig...