Background Bacterial meningitis and meningoencephalitis are associated with devastating neuroinflammation. We and others have demonstrated the importance of glial cells in the initiation of immune responses to pathogens invading the central nervou...
Marriott, Ian, Jeffries, Austin M., Suptela, Alexander J.
Date Created
2022
Subjects--Topical
Herpes simplex virus, DNA
Description
The mechanisms by which glia respond to viral central nervous system (CNS) pathogens are now becoming apparent with the demonstration that microglia and astrocytes express an array of pattern recognition receptors that include intracellular RNA an...