Search results
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Title
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Artificial immune cell, AI-cell, a new tool to predict interferon production by peripheral blood monocytes in response to nucleic acid nanoparticles
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Author
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Afonin, Kirill A., Chandler, Morgan, Halman, Justin
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Date Created
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2022
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Subjects--Topical
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Nucleic acids, Chemistry
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Description
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Nucleic acid nanoparticles, or NANPs, rationally designed to communicate with the human immune system, can offer innovative therapeutic strategies to overcome the limitations of traditional nucleic acid therapies. Each set of NANPs is unique in th...
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Title
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Biomotors, viral assembly, and RNA nanobiotechnology : current achievements and future directions
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Author
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Robland, Lewis, Beasock, Damian, Afonin, Kirill A., Schlick, Tamar
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Date Created
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2022
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Subjects--Topical
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Viruses, Nanotechnology
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Description
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The International Society of RNA Nanotechnology and Nanomedicine (ISRNN) serves to further the development of a wide variety of functional nucleic acids and other related nanotechnology platforms. To aid in the dissemination of the most recent adv...
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Title
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Characterization of cationic bolaamphiphile vesicles for sirna delivery into tumors and brain
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Author
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Afonin, Kirill A., Kim, Taejin, Gupta, Kshitij
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Date Created
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2020
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Subjects--Topical
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Nucleic acids, Chemistry
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Description
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Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). Howeve...
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Title
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Demonstrating the synthesis and antibacterial properties of nanostructured silver
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Author
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Rolband, Lewis, Godakhindi, Varsha, Vivero-Escoto, Juan L., Afonin, Kirill A.
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Date Created
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2023
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Subjects--Topical
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Antibacterial agents, Silver
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Description
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Investigating and understanding novel antibacterial agents is a necessary task as there is a constant increase in the number of multidrug-resistant bacterial species. The use of nanotechnology to combat drug-resistant bacteria is an important rese...
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Title
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Exosome mediated delivery of functional nucleic acid nanoparticles (NANPs)
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Author
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Afonin, Kirill A., Ke, Weina
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Date Created
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2020
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Subjects--Topical
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Nucleic acids, Chemistry
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Description
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RNAi-based technologies have shown biomedical potential; however, safe and efficient delivery of RNA remains a barrier for their broader clinical applications. Nucleic acid nanoparticles (NANPs) programmed to self-assemble and organize multiple th...
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Title
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Functionally-interdependent shape-switching nanoparticles with controllable properties
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Author
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Halman, Justin, Khisamutdinov, Emil F., Afonin, Kirill A., Satterwhite, Emily, Roark, Brandon, Chandler, Morgan, Ivanina, Anna, Viard, Mathias, Bindewald, Eckart, Kasprzak, Wojciech K., Panigaj, Martin, Bui, My N., Lu, Jacob S., Miller, Johann, Shapiro, Bruce A., Dobrovolskaia, Marina A.
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Subjects--Topical
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Nucleic acids, Nanotechnology
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Description
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We introduce a new concept that utilizes cognate nucleic acid nanoparticles which are fully complementary and functionally-interdependent to each other. In the described approach, the physical interaction between sets of designed nanoparticles ini...
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Title
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Functionally-interdependent shape-switching nanoparticles with controllable properties
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Author
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Afonin, Kirill A., Halman, Justin, Chandler, Morgan
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Date Created
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2017
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Subjects--Topical
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Nucleic acids, Chemistry
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Description
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We introduce a new concept that utilizes cognate nucleic acid nanoparticles which are fully complementary and functionally-interdependent to each other. In the described approach, the physical interaction between sets of designed nanoparticles ini...