Search results
-
-
Title
-
GSI treatment preserves protein synthesis in C2C12 myotubes
-
Author
-
Arthur, Susan, Huot, Joshua, Marino, Joseph S., Thompson, Brian, McMullen, Charlotte
-
Subjects--Topical
-
Muscle proteins, Cells
-
Description
-
It has been demonstrated that inhibiting Notch signaling through γ-secretase inhibitor (GSI) treatment increases myogenesis, AKT/mTOR signaling, and muscle protein synthesis (MPS) in C2C12 myotubes. The purpose of this study was to determine if GS...