Search results | J. Murrey Atkins Library

Title: Insights Into Plasmodium Genetic Changes Related To Malaria Interventions
Author: Dieng, Cheikh
Date Created: 2023
Subjects--Topical: Biology, Parasitology, Genetics
Description: Over 80% of all malaria deaths occur in children under 5 years of age. Malaria controlstrategies have been progressively shifted to specific populations and/or areas to maximize effectiveness. Malaria is a significant public health problem in Ghan...

Title: Integration of phylogenomics and molecular modeling reveals lineage-specific diversification of toxins in scorpions
Author: Janies, Daniel, Rush, Nathaniel, Witter, Zachary, Williams, John
Date Created: 2018
Subjects--Topical: Genomics, Biology
Description: Scorpions have evolved a variety of toxins with a plethora of biological targets, but characterizing their evolution has been limited by the lack of a comprehensive phylogenetic hypothesis of scorpion relationships grounded in modern, genome-scale...

Title: JED: a Java essential dynamics program for comparative analysis of protein trajectories
Author: Jacobs, Donald J., Ramaprasad, Azhagiya Singam Ettayapuram, David, Charles C.
Date Created: 2017
Subjects--Topical: Biology, Proteins
Description: Background: Essential Dynamics (ED) is a common application of principal component analysis (PCA) to extract biologically relevant motions from atomic trajectories of proteins. Covariance and correlation based PCA are two common approaches to dete...

Title: JEDi: Java essential dynamics inspector - a molecular trajectory analysis toolkit
Author: Jacobs, Donald J., Avery, Chris
Date Created: 2021
Subjects--Topical: Biology, Proteins
Description: Background Principal component analysis (PCA) is commonly applied to the atomic trajectories of biopolymers to extract essential dynamics that describe biologically relevant motions. Although application of PCA is straightforward, specialized soft...

Title: Linear mitochondrial genome in Anthozoa (Cnidaria) : a case study in Ceriantharia
Author: Reitzel, Adam M., Stampar, Sergio N., Macrander, Jason
Date Created: 2019
Subjects--Topical: Gene expression, Biology
Description: Sequences and structural attributes of mitochondrial genomes have played a critical role in the clarification of relationships among Cnidaria, a key phylum of early-diverging animals. Among the major lineages of Cnidaria, Ceriantharia (tube anemon...

Title: Long-term study of changes in microbiota in a Cystic Fibrosis patient
Author: Stokell, Joshua
Date Created: 2013
Subjects--Topical: Biology, Microbiology
Description: Application of culture-independent techniques have revealed the presence of more types of bacteria than were previously thought, which led to the current description of Cystic Fibrosis (CF) being a polymicrobial disease. We know this polymicrobial...

Title: MACROPHAGES EXPRESSING NEUROPILIN-1 AND BREAST TUMOR PROGRESSION
Author: Helms, Rachel
Date Created: 2015
Subjects--Topical: Biology
Description: Human breast carcinoma is the most commonly diagnosed cancer in women in the United States with patient mortality primarily resulting from metastasis of breast cancer cells to distant organs. Immune cells, including macrophages, are involved in ca...

Title: MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Author: Grover, Priyanka
Date Created: 2019
Subjects--Topical: Biology
Description: In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...

Title: Mechanisms of acclimation and adaptation in the sea urchin Echinometra sp. EZ
Author: Ketchum, Remi
Date Created: 2017
Subjects--Topical: Biology
Description: Climate change has resulted in warming of coastal aquatic habitats around the world at almost every latitude, threatening ecosystems with a significant loss in biodiversity and occurring at a rate that may exceed species’ ability to adapt. Underst...

Title: Microbial diversity and activity in the Nematostella vectensis holobiont : insights from 16S rRNA gene sequencing, isolate genomes, and a pilot-scale survey of gene expression
Author: Reitzel, Adam M., Har, Jia Y., Helbig, Tim
Date Created: 2015
Subjects--Topical: Gene expression, Biology
Description: We have characterized the molecular and genomic diversity of the microbiota of the starlet sea anemone Nematostella vectensis, a cnidarian model for comparative developmental and functional biology and a year-round inhabitant of temperate salt mar...

Title: Multisensory integration by polymodal sensory neurons dictates larval settlement in a brainless cnidarian larva
Author: Birch, Sydney, Plachetzki, David
Date Created: 2023
Subjects--Topical: Biology, Developmental biology
Description: Multisensory integration (MSI) combines information from more than one sensory modality to elicit behaviours distinct from unisensory behaviours. MSI is best understood in animals with complex brains and specialized centres for parsing different m...

Title: NOVEL ROLES OF MICRORNAS IN HEPATITIS C
Author: Sendi, Hossein
Date Created: 2013
Subjects--Topical: Virology, Biology
Description: Approximately, 170 million people are infected by hepatitis C virus (HCV) worldwide, and of these, nearly 85% will develop chronic hepatitis C (CHC). Despite finding new anti-viral treatment that increase response rate from 45 % to 65-70 %, invest...

Title: Newly described cytosolic pattern recognition receptors mediate inflammatory glial responses to neurotropic viruses
Author: Furr, Samantha
Date Created: 2012
Subjects--Topical: Immunology, Biology
Description: The rapid onset of potentially lethal neuroinflammation is a defining feature of viral encephalitis. Glial cells are ideally positioned to respond to invading pathogens of the central nervous system (CNS) and produce key inflammatory mediators fol...

Title: Nonsegmented negative strand RNA viruses: viral RNA cap methylation and potential applications as an anticancer therapy
Author: Murphy, Andrea
Date Created: 2012
Subjects--Topical: Virology, Biology
Description: The viruses of the order Mononegavirales include important human, animal, and plant pathogens and additionally, have great potential as vaccine, oncolytic and gene therapy vectors. This dissertation focuses on two prototypic Mononegavirales, vesic...

Title: Oral Microbiome Signature for Hematological Cancer
Author: Langdon, Holden
Date Created: 2020
Subjects--Topical: Biology
Description: BackgroundThe endogenous microbiome of healthy individuals in the oral cavity is diverse, representing over 700 different bacterial species. Some of these species may become opportunistic if certain elements in the microenvironment and host-respon...

Title: Origin of the animal circadian clock : diurnal and light-entrained gene expression in the sponge amphimedon queenslandica
Author: Reitzel, Adam M., Jindrich, Katia, Roper, Kathrein E.
Date Created: 2017
Subjects--Topical: Evolution (Biology), Biology
Description: The circadian clock is a molecular network that coordinates organismal behavior and physiology with daily environmental changes in the day-night cycle. In eumetazoans (bilaterians + cnidarians), this network appears to be largely conserved, yet di...

Title: Patch dynamics modeling framework from pathogens' perspective : Unified and standardized approach for complicated epidemic systems
Author: Janies, Daniel, Chen, Shi, Lo, Eugenia, Dulin, Michael
Date Created: 2020
Subjects--Topical: Communicable diseases, Biology
Description: Mathematical models are powerful tools to investigate, simulate, and evaluate potential interventions for infectious diseases dynamics. Much effort has focused on the Susceptible-Infected-Recovered (SIR)-type compartment models. These models consi...

Title: Periostin and TGFBI in Breast Cancer Progression
Author: Phelps, Michelle
Date Created: 2015
Subjects--Topical: Biology, Cytology
Description: Dynamic interactions between cancer cells, supportive stromal cells, the extracellular matrix (ECM), and the immune system are critical to breast cancer progression. Periostin is an ECM protein correlated to poor outcomes in breast cancer. Periost...

Title: Phylogeny of echinoderm hemoglobins
Author: Janies, Daniel, Linchangco, Gregorio V., Jr.
Date Created: 2015
Subjects--Topical: Genomics, Biology
Description: Background Recent genomic information has revealed that neuroglobin and cytoglobin are the two principal lineages of vertebrate hemoglobins, with the latter encompassing the familiar myoglobin and alpha-globin/beta-globin tetramer hemoglobin, and ...

Title: Phylotranscriptomic analysis uncovers a wealth of tissue inhibitor of metalloproteinases variants in echinoderms
Author: Janies, Daniel, Clouse, Ronald M., Linchangco, Gregorio V., Jr.
Date Created: 2015
Subjects--Topical: Genomics, Biology
Description: Tissue inhibitors of metalloproteinases (TIMPs) help regulate the extracellular matrix (ECM) in animals, mostly by inhibiting matrix metalloproteinases (MMPs). They are important activators of mutable collagenous tissue (MCT), which have been exte...