Search results | J. Murrey Atkins Library

Title: MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Author: Grover, Priyanka
Date Created: 2019
Subjects--Topical: Biology
Description: In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...

Title: Mechanisms of acclimation and adaptation in the sea urchin Echinometra sp. EZ
Author: Ketchum, Remi
Date Created: 2017
Subjects--Topical: Biology
Description: Climate change has resulted in warming of coastal aquatic habitats around the world at almost every latitude, threatening ecosystems with a significant loss in biodiversity and occurring at a rate that may exceed species’ ability to adapt. Underst...

Title: NOVEL ROLES OF MICRORNAS IN HEPATITIS C
Author: Sendi, Hossein
Date Created: 2013
Subjects--Topical: Virology, Biology
Description: Approximately, 170 million people are infected by hepatitis C virus (HCV) worldwide, and of these, nearly 85% will develop chronic hepatitis C (CHC). Despite finding new anti-viral treatment that increase response rate from 45 % to 65-70 %, invest...

Title: Newly described cytosolic pattern recognition receptors mediate inflammatory glial responses to neurotropic viruses
Author: Furr, Samantha
Date Created: 2012
Subjects--Topical: Immunology, Biology
Description: The rapid onset of potentially lethal neuroinflammation is a defining feature of viral encephalitis. Glial cells are ideally positioned to respond to invading pathogens of the central nervous system (CNS) and produce key inflammatory mediators fol...

Title: Nonsegmented negative strand RNA viruses: viral RNA cap methylation and potential applications as an anticancer therapy
Author: Murphy, Andrea
Date Created: 2012
Subjects--Topical: Virology, Biology
Description: The viruses of the order Mononegavirales include important human, animal, and plant pathogens and additionally, have great potential as vaccine, oncolytic and gene therapy vectors. This dissertation focuses on two prototypic Mononegavirales, vesic...

Title: Notch Serves as a Molecular Brake on Myogenesis, Protein Synthesis, and Growth in Skeletal Muscle
Author: Huot, Joshua
Date Created: 2018
Subjects--Topical: Molecular biology, Kinesiology
Description: Aging can be accompanied by aggressive loss of muscle mass (sarcopenia) and is a primary prognosticator for the reduced capacity of the elderly to accomplish basic activities of daily living. Several mechanisms within skeletal muscle lead to devel...

Title: Oral Microbiome Signature for Hematological Cancer
Author: Langdon, Holden
Date Created: 2020
Subjects--Topical: Biology
Description: BackgroundThe endogenous microbiome of healthy individuals in the oral cavity is diverse, representing over 700 different bacterial species. Some of these species may become opportunistic if certain elements in the microenvironment and host-respon...

Title: Periostin and TGFBI in Breast Cancer Progression
Author: Phelps, Michelle
Date Created: 2015
Subjects--Topical: Biology, Cytology
Description: Dynamic interactions between cancer cells, supportive stromal cells, the extracellular matrix (ECM), and the immune system are critical to breast cancer progression. Periostin is an ECM protein correlated to poor outcomes in breast cancer. Periost...

Title: Phenotypic Plasticity and Genetic Variation in Two Diverse Groups of Mollusks
Author: Furr, Denise
Date Created: 2023
Subjects--Topical: Natural history--Classification, Physiology, Zoology
Description: Mollusks are a highly diverse phylum with some of the most extremes of body forms from wormlike Aplacophora to tentacled cephalopods. The relationship between phenotype and phylogeny is studied here in two very different groups of mollusks, the bi...

Title: Pleiotropic effects on the transcriptome and genome of transgenic soybeans resulting from transgene integration and expression in seed tissue
Author: Lambirth, Kevin
Date Created: 2015
Subjects--Topical: Molecular biology, Biology, Bioinformatics
Description: The seeds of the common soybean (Glycine max) produce and store large amounts of protein, making them an appealing bioreactor for producing valuable recombinant proteins at high levels. However, the effects of accumulating recombinant protein at h...

Title: Polymer Mediated Delivery of Oligonucleotide and Trans Genes Toward More Efficient and Specific Therapies for Dystrophinopathies and Dystroglycanopathies
Author: Tucker, Jason
Date Created: 2014
Subjects--Topical: Molecular biology, Biology, Neurosciences
Description: Muscular dystrophies are genetic disorders caused by mutations in more than 30 genes, with no cure or effective treatment. Duchenne muscular dystrophy (DMD) is caused by frame-shift mutations in the dystrophin gene with little or no functional dys...

Title: Polystyrene particle uptake and their potential to act as a trojan horse to oysters (Crassostrea virginica)
Author: Gaspar, Tamara
Date Created: 2017
Subjects--Topical: Environmental sciences, Ecology, Cytology
Description: The global annual usage of plastics has increased dramatically over the last decade. Polystyrene is the fourth most common plastic material produced annually due to its many versatile applications. Consequently, there has been a coinciding increas...

Title: Prevalence of Plasmodium vivax in Duffy-Negative Individuals Across Broad Regions of Ethiopia
Author: Little, Ebony
Date Created: 2023
Subjects--Topical: Biology
Description: Plasmodium parasites replicate asexually in the human host, and, in each replication cycle, a portion of the asexual stages develops into sexual gametocytes. The proportion of infections that carries gametocytes is a proxy for human-to-mosquito tr...

Title: Production of Immunomodulatory Proteins in Glycine max for use in Diagnostics and as Therapeutics
Author: Powell, Rebecca
Date Created: 2010
Subjects--Topical: Molecular biology
Description: ABSTRACTREBECCA DIANE POWELL. Production of Immunomodulatory Proteins in Glycine max for Use in Diagnostics and as Therapeutics. (Under the direction of DR. KENNETH L. BOST) Immunomodulatory proteins can be utilized in diagnostic assays, as tolera...

Title: RANK-L expression in Staphylococcus aureus- induced osteomyelitis, therapeutic intervention using nanotechnology and use of UV-killed bacteria as an osteoconductive coating for biomaterials.
Author: Somayaji, Shankari
Date Created: 2009
Subjects--Topical: Microbiology
Description: Staphylococcus aureus is responsible for approximately 80% of all cases of human osteomyelitis. RANK-L is an essential signal produced by osteoblasts and is required for full osteoclastic differentiation. PGE₂ - induced bone resorption involves bo...

Title: RECIPROCAL REGULATION OF MYC AND MICRORNA MIR-308 DURING DROSOPHILA EMBRYOGENESIS
Author: Daneshvar, Kaveh
Date Created: 2012
Subjects--Topical: Molecular biology, Biology, Genetics
Description: Myc is a conserved transcription factor with a role in the regulation of genes that are involved in growth and development. The abundance of Myc protein in the cells must be exquisitely controlled to avoid growth abnormalities caused by too much o...

Title: REGULATION OF APE1 BY NEIL3 ZINC FINGER-GRF REPEAT ON SINGLE-STRANDED DNA
Author: Ha, Anh
Date Created: 2020
Subjects--Topical: Molecular biology, Cytology
Description: Base excision repair (BER) is a critical pathway in repairing single base lesions caused by oxidation, deamination, and alkylation. NEIL3 is a DNA glycosylase which functions in initiating BER pathway by recognizing and removing damaged bases. Alt...

Title: ROLE OF AQUAPORINS DURING HEPATOCELLULAR CARCINOMA INITIATION AND PROGRESSION
Author: Mattocks, Matthew
Date Created: 2010
Subjects--Topical: Molecular biology, Cytology, Oncology
Description: Aquaporins (AQPs) are ubiquitously expressed proteinaceous water channels involved in numerous physiological processes including bile production and apoptosis. Aquaporins 8 and 9 are expressed in hepatocytes, and are down regulated in a rat model ...

Title: ROLE OF THE NOVEL DNA SENSORS cGAS, IFI16, AND ZBP1, DURING VIRAL INFECTIONS IN GLIA
Author: Jeffries, Austin
Date Created: 2020
Subjects--Topical: Immunology, Virology, Neurosciences
Description: Viral central nervous system (CNS) infections can lead to life threatening encephalitis and long-term neurological deficits in survivors. Resident CNS cell types, such as astrocytes and microglia, are known to produce key inflammatory and antivira...

Title: Regulation of Myc and its Localization to Histone Locus Body in Drosophila
Author: Khan, Abid
Date Created: 2012
Subjects--Topical: Molecular biology, Biology, Developmental biology
Description: Myc is a transcriptional factor required for normal growth and development in vertebrates and invertebrates alike. Loss of function mutations in Myc can cause embryonic lethality in mammals and larval death in flies whereas an increase in its acti...