Search results
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Title
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ROLE OF AQUAPORINS DURING HEPATOCELLULAR CARCINOMA INITIATION AND PROGRESSION
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Author
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Mattocks, Matthew
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Date Created
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2010
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Subjects--Topical
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Molecular biology, Cytology, Oncology
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Description
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Aquaporins (AQPs) are ubiquitously expressed proteinaceous water channels involved in numerous physiological processes including bile production and apoptosis. Aquaporins 8 and 9 are expressed in hepatocytes, and are down regulated in a rat model ...
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Title
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Role of Nonmuscle Myosin II in Hepatic Stellate Cell Activation
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Author
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Moore, Cathy
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Date Created
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2009
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Subjects--Topical
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Molecular biology
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Description
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The hepatic stellate cell (HSC) plays a pivotal role in the development of hepatic fibrosis. Regulation of liver microcirculation is a complex system where blood flow is under systemic and sinusoidal control. Upon a fibrogenic stimulus, quiescent ...
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Title
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SELECTIVE HEATING OF VASCULAR STRUCTURES TO CREATE CONTRAST IN MEDICAL MID-IR IMAGES
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Author
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Case, Jason
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Date Created
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2015
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Subjects--Topical
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Optics, Diagnostic imaging
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Description
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The goal of this study is to develop an enhanced mid-IR imaging modality for mapping vascular structures. This imaging technique is intended for real-time use by medical professionals during surgical procedures such as tumor removal and vascular m...
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Title
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SINGLE-STEP, REDUCED SHEAR, MICROFLUIDIC EXTRUSION OF BLOOD BRAIN BARRIER
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Author
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Wetzel, Isaac
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Date Created
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2019
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Subjects--Topical
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Biomedical engineering
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Description
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Three-dimensional (3D) bioprinting of living structures with cell-laden biomaterials has been achieved in vitro, however, central nervous system tissues have been limited by the low viability printing of cerebral vessels, using conventional printi...
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Title
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THE ROLE OF TRANSLESION SYNTHESIS POLYMERASES REV1 AND POL η IN DNA DAMAGE RESPONSE
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Author
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McLeod, Melissa
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Date Created
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2016
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Subjects--Topical
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Molecular biology, Biology, Cytology
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Description
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Our cells endure continuous challenges from byproducts of endogenous metabolic processes as well as outside sources such as UV light and environmental polltants. The DNA Damage Response (DDR) helps organisms cope with damage and coordinate an appr...
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Title
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THE ROLE OF XRCC1 AND POLYMERASE BETA IN GENOME INTEGRITY IN XENOPUS EGG EXTRACTS
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Author
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Cupello, Steven
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Date Created
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2019
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Subjects--Topical
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Molecular biology, Biology, Cytology
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Description
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Cells of organisms are constantly exposed to genomic insults such as oxidative stress from endogenous sources or environmental agents. Oxidative stress induces oxidative DNA damage such as apurinic/apyrimidinic (AP) sites, single-strand breaks (SS...
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Title
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The Local Dynamics of Basement Membrane Breaching During Cancer Cell Invasion
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Author
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Nazari, Shayan
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Date Created
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2022
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Subjects--Topical
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Biology
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Description
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Solid tumor metastasis is the leading cause of cancer-related mortality. Cancer invasion through the confining basement membrane (BM) is the initial step in tumor dissemination and metastasis, and it represents a key diagnostic feature of cancer. ...
