Search results
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Title
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Detrimental brain inflammation and the role of the interleukin 10 family members
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Author
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Burmeister, Amanda
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Date Created
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2019
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Subjects--Topical
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Biology
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Description
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Resident brain cells recognize pathogens and can initiate and/or regulate inflammation. Indeed, we have shown that stimulated glial cells rapidly produce inflammatory mediators, followed by the late production of anti-inflammatory cytokines such a...
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Title
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Dissecting functional differences in Hsp70 isoforms in nematostella vectensis
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Author
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Waller, Shawn
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Date Created
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2018
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Subjects--Topical
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Molecular biology
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Description
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Heat shock protein 70s (Hsp70s) are a highly conserved class of molecular chaperones that are involved in cellular processes in all organisms such as stress response, homeostatic maintenance, and cell cycle progression. The organism Nematostella v...
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Title
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EXPERIMENTAL EVOLUTION OF ONCOLYTIC VESICULAR STOMATITIS VIRUSES IN CANCER CELLS
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Author
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Seegers, Sara
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Date Created
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2019
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Subjects--Topical
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Molecular biology, Virology, Biology
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Description
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Vesicular stomatitis virus (VSV) based oncolytic viruses are promising agents against various cancers. We have shown that pancreatic ductal adenocarcinoma (PDAC) cell lines exhibit great diversity in susceptibility and permissibility to VSV. Here,...
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Title
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Exploring the Immune System using Hybrid Cube Nanoparticles
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Author
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McMillan, Jessica
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Date Created
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2021
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Subjects--Topical
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Biochemistry, Nanotechnology, Biology
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Description
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Nano-sized cubes made from nucleic acid material (NANPs) are ideal scaffolds for therapeutic nucleic acids (TNAs). Both utilize sequence specificity through base-pairing, providing controlled strand interaction, stability, and targeted targeting d...
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Title
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Fibroblast-driven Fibrosis and Inflammation in Breast Cancer Progression
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Author
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Samuels, Courtney
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Date Created
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2022
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Subjects--Topical
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Biology
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Description
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Breast cancer progression is promoted by both local inflammation and fibrosis. Indeed,accumulation of fibrous collagen is an independent prognosis marker of breast cancer. However, the mechanisms underlying the interplay between fibroblasts, infla...
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Title
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Fungal Treatments for Lignocellulosic Bioconversion
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Author
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Giles, Richard
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Date Created
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2013
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Subjects--Topical
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Power resources, Biology
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Description
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Four studies were conducted to develop an innovative application of fungal biopulping technologies to improve commercialization of lignocellulosic ethanol biofuel production using sustainable waste products. The first study focused on evaluation a...