Search results | J. Murrey Atkins Library

Title: Development of a Surface Enhanced Raman Spectroscopy-based Assay to Detect Malaria Biomarkers in Blood
Author: Hamm, Logan
Date Created: 2020
Subjects--Topical: Chemistry
Description: Malaria is an infectious disease that affects many lives around the world and eradication efforts are focused on controlling the disease transmission; which requires early diagnosis of the infection before the onset of symptoms, i.e. at the asympt...

Title: Development of nanoparticle-based approaches for the treatment and imaging of pancreatic cancer
Author: Tarannum, Mubin
Date Created: 2020
Subjects--Topical: Nanoscience, Chemistry
Description: Pancreatic ductal adenocarcinoma (PDAC) is a type of exocrine pancreatic cancer which accounts for over 90% of cases. PDAC is the fourth-leading cause of cancer-related mortality in the United States with a 5-year survival rate of 9% with little t...

Title: ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
Author: Okwei, Elleansar
Date Created: 2016
Subjects--Topical: Chemistry, Biology, Biochemistry
Description: The fight against bacterial infection is one of the most important branches of modern medicine. Due to the emergence of strains of antibiotic-resistant bacteria, researchers have been presented with complex challenges in an effort to combat these ...

Title: Early Detection of Malaria Parasitic RNA Through an Amplification-Free Surface-Enhanced Raman Spectroscopy Biosensor
Author: Blackwell, Ashley
Date Created: 2022
Subjects--Topical: Chemistry
Description: Malaria retains its position as one of the most highly transferable diseases throughout the world today, with current efforts focused on controlling its spread. A sensitive, asymptomatic-stage detection method is needed to diagnose malaria before ...

Title: Editorial for the special issue on nucleic acid architectures for therapeutics, diagnostics, devices and materials
Author: Afonin, Kirill A., Halman, Justin
Date Created: 2019
Subjects--Topical: Nucleic acids, Chemistry

Title: Effects of Weathering on Performance of Intumescent Coatings for Structure Fire Protection in the Wildland-Urban Interface
Author: Bahrani, Babak
Date Created: 2015
Subjects--Topical: Chemistry, Polymers, Materials science, Wood
Description: The objective of this study was to investigate the effects of weathering on the performance of intumescent fire-retardant coatings on wooden products. The weathering effects included primary (solar irradiation, moisture, and temperature) and secon...

Title: Electrochromic, Electrofluorochromic, and Photoactive Properties of Thiazolothiazole-Based, Multifunctional Materials
Author: Adams, Tyler
Date Created: 2023
Subjects--Topical: Chemistry, Nanoscience
Description: There have been an increasing number of materials developed that show multifunctional chromogenic properties (such as electrochromism, electrofluorochromism, or photochromism), but to date, few materials have shown all three properties. Materials ...

Title: Exceptional New Reagents for Bioconjugation
Author: Garmon, Corey
Date Created: 2016
Subjects--Topical: Chemistry, Biochemistry
Description: At about the turn of this century the term "click" chemistry came into the common vernacular amongst chemists. "Click" is used to describe reactions that are "spring-loaded" and proceed well in a predictable manner, with no offensive byproduct and...

Title: Exosome mediated delivery of functional nucleic acid nanoparticles (NANPs)
Author: Afonin, Kirill A., Ke, Weina
Date Created: 2020
Subjects--Topical: Nucleic acids, Chemistry
Description: RNAi-based technologies have shown biomedical potential; however, safe and efficient delivery of RNA remains a barrier for their broader clinical applications. Nucleic acid nanoparticles (NANPs) programmed to self-assemble and organize multiple th...

Title: Expanding structural space for immunomodulatory nucleic acid nanoparticles (NANPs) via spatial arrangement of their therapeutic moieties
Author: Afonin, Kirill A., Chandler, Morgan, Rolband, Lewis
Date Created: 2022
Subjects--Topical: Nucleic acids, Chemistry
Description: Different therapeutic nucleic acids (TNAs) can be unified in a single structure by their elongation with short oligonucleotides designed to self-assemble into nucleic acid nanoparticles (NANPs). With this approach, therapeutic cocktails with preci...

Title: Exploring the photophysics and photocatalytic properties of platinum and palladium nanoparticles
Author: Major, Kevin
Date Created: 2012
Subjects--Topical: Nanoscience, Chemistry, Chemistry, Physical and theoretical
Description: Platinum and Palladium nanoparticles are important nanoscale materials for a variety of materials science and industrial applications. The presented research covers a broad spectrum of these unique nanoparticles, from their synthesis and character...

Title: First step towards larger DNA-based assemblies of fluorescent silver nanoclusters: template design and detailed characterization of optical properties
Author: Afonin, Kirill A., Shevchenko, Oleg
Date Created: 2019
Subjects--Topical: Nucleic acids, Chemistry
Description: Besides being a passive carrier of genetic information, DNA can also serve as an architecture template for the synthesis of novel fluorescent nanomaterials that are arranged in a highly organized network of functional entities such as fluorescent ...

Title: Folate Receptor-Specific, Redox-Responsive Mesoporous Silica Nanoparticles for the Simultaneous Delivery of Cisplatin and Gemcitabine to Treat Cancer
Author: Fink, Eric
Date Created: 2016
Subjects--Topical: Materials science, Chemistry, Biochemistry
Description: Nanoparticles are an innovative platform for cancer treatment that reduces systemic toxicity and allows for active targeting of tumor sites to enhance the therapeutic efficacy. Mesoporous silica nanoparticles (MSNs) have emerged as an attractive d...

Title: Functionally-interdependent shape-switching nanoparticles with controllable properties
Author: Afonin, Kirill A., Halman, Justin, Chandler, Morgan
Date Created: 2017
Subjects--Topical: Nucleic acids, Chemistry
Description: We introduce a new concept that utilizes cognate nucleic acid nanoparticles which are fully complementary and functionally-interdependent to each other. In the described approach, the physical interaction between sets of designed nanoparticles ini...

Title: Green Synthesis of Cellulose Graft Copolymers for Anion Exchange Water Purification
Author: Schmal, Stephen
Date Created: 2022
Subjects--Topical: Chemistry
Description: This thesis describes the synthesis and characterization of novel cellulose graft copolymers that are used for the purification of drinking water. These nanomaterials function as bottle-brush anion-exchange resins with repeating quaternary ammoniu...

Title: Halogenated Tags for the Investigation of Enzyme Specificity
Author: Houde, Hailey
Date Created: 2023
Subjects--Topical: Biochemistry, Chemistry
Description: The bacterial enzyme undecaprenyl pyrophosphate synthase (UppS) is present in most prokaryotes and is needed for bacterial survival. UppS produces the essential lipid carrier, bactoprenyl monophosphate (BP). BP is critical for the structural integ...

Title: Hexacoordinate Silicon Complexes as Cathodic Colorants
Author: Peloquin, Derek
Date Created: 2016
Subjects--Topical: Nanoscience, Chemistry, Chemistry, Inorganic
Description: Electrochemical and spectroelectrochemical characterization of hexacoordinate polypyridine silicon complexes show that they are fitting candidates for electrochromic applications. Tris(bipyridine)silicon(IV), [Si(bpy)3]+4, is colorless in acetonit...

Title: Hypercoordinate Silicon CNC-Pincer Complexes for Electronic Devices
Author: Earnhardt, Adam
Date Created: 2022
Subjects--Topical: Chemistry, Chemistry, Organic, Materials science
Description: Previous studies have demonstrated hexacoordinate silicon pincer complexes to be attractive candidates for efficient electron and hole transport layers in organic electronic devices. This work expands the field by incorporating carbon-nitrogen-car...

Title: IDENTIFICATION OF EPITHELIAL OVARIAN TUMOR SPECIFIC APTAMERS THAT BIND AND INTERNALIZE INTO TARGET CELLS
Author: Benedetto, Gregory
Date Created: 2015
Subjects--Topical: Chemistry, Biology
Description: New clinical tools that aid in the early diagnosis of ovarian malignancies will significantly help reduce mortality and improve current long-term survival rates. The objective of the work presented here was to identify ovarian tumor specific singl...

Title: INTERFACE STUDY OF SPIRO-OMETAD ON PASSIVATED P-, N-, AND N+-Si(111) FOR USE IN TANDEM PEROVSKITE/SILICON SOLAR CELL DEVICES
Author: Nguyen, Li
Date Created: 2015
Subjects--Topical: Chemistry, Chemistry, Physical and theoretical, Renewable energy sources
Description: The organic semiconductor 2,2’,7,7’-tetrakis-(N,N-di-p-methoxyphenylamine)9,9’-spirobifluorene (Spiro-OMeTAD) contact properties are studied on p-, n-, and n+-type silicon. Spiro-OMeTAD is a solid state hole conductor that has notably been used in...