Search results
- Title
- Collateral changes in susceptibility of Burkholderia multivorans
- Author
- Flanagan, Jerilyn
- Date Created
- 2019
- Subjects--Topical
- Biology, Microbiology
- Description
- Antibiotic resistant bacteria, particularly in chronic infections, are difficult and costly to treat, so research into detection, identification, and treatment options is critical. Susceptibility measurement must accurately reflect the degree to w...
- Title
- Common Dietary and Environmental Compounds Promote a Leukemic Translocation in Hematopoietic Stem Cells and Differentiated Cells
- Author
- Vestal, Carol
- Date Created
- 2016
- Subjects--Topical
- Molecular biology, Biology, Genetics
- Description
- Maternal exposure to topoisomerase II (topoII) inhibitors that are biochemically similar to the chemotherapeutic drug etoposide may promote infant acute leukemia. Several studies have shown that common dietary bioflavonoids as well as benzene meta...
- Title
- Comparative analysis of Nitrosococcus genomes; isolation, physiological and genomic characterization of the new ammonia-oxidizing species Nitrosococcus wardiae, strain D1FHST; and molecular studies towards a better understanding of ammonia-dependent chemolithotrophy
- Author
- Wang, Lin
- Date Created
- 2016
- Subjects--Topical
- Molecular biology, Biology, Genetics
- Description
- Obligate aerobic chemolithoautotrophic ammonia-oxidzing bacteria (AOB) derive energy and reductant needed for growth solely from the oxidation of ammonia to nitrite thereby facilitating the process of nitritation. A strain of an ammonia-oxidizing ...
- Title
- Content and sentiment surveillance (CSI) : A critical component for modeling modern epidemics
- Author
- Janies, Daniel, Chen, Shi, Zhang, Dongsong
- Date Created
- 2023
- Subjects--Topical
- Communicable diseases, Biology
- Description
- Comprehensive surveillance systems are the key to provide accurate data for effective modeling. Traditional symptom-based case surveillance has been joined with recent genomic, serologic, and environment surveillance to provide more integrated dis...
- Title
- Convergent shifts in host-associated microbial communities across environmentally elicited phenotypes
- Author
- Reitzel, Adam M., Carrier, Tyler J.
- Date Created
- 2018
- Subjects--Topical
- Evolution (Biology), Biology
- Description
- Morphological plasticity is a genotype-by-environment interaction that enables organisms to increase fitness across varying environments. Symbioses with diverse microbiota may aid in acclimating to this variation, but whether the associated bacter...
- Title
- Cranial Capacity Variation of Pleistocene Homo and Possible Speciation Events
- Author
- Hudock, Autumn
- Date Created
- 2021
- Subjects--Topical
- Biology, Paleontology, Evolutionary developmental biology
- Description
- The field of paleoanthropology is tasked with studying the morphology of extinct hominins using fossilized remains. To study the evolution of the human brain, researchers use endocast data derived from fossil skulls, in order to assess when and ho...
- Title
- DNA extraction method plays a significant role when defining bacterial community composition in the marine invertebrate Echinometra mathaei
- Author
- Reitzel, Adam M., Ketchum, Remi, Carrier, Tyler J.
- Date Created
- 2018
- Subjects--Topical
- Bacteria, Biology
- Description
- The microbial assemblages of marine organisms play fundamental biological roles in their eukaryotic hosts. Studies aimed at characterizing this diversity have increased over the last decade and with the availability of high-throughput sequencing, ...
- Title
- Daily cycle in oxygen consumption by the sea anemone Nematostella vectensis Stephenson
- Author
- Reitzel, Adam M., Maas, Amy E., Jones, Ian T.
- Date Created
- 2016
- Subjects--Topical
- Gene expression, Biology
- Description
- In bilaterian animals, the circadian clock is intimately involved in regulating energetic metabolism. Although cnidarians exhibit diel behavioral rhythms including cycles in locomotor activity, tentacle extension and spawning, daily cycles in cnid...
- Title
- Design and Modulation of Novel Chemical Probes for RNA SHAPE Analysis: Water Soluble Isatoic Anhydrides and Nicotinic Acid Imidazolides
- Author
- Fessler, Adam
- Date Created
- 2021
- Subjects--Topical
- Chemistry, Biology
- Description
- The growing interest in RNA biology, along with an expansion in computational capabilities, throughput, and sensitivity has provided researchers new tools to probe RNA. RNA selective 2′-hydroxy acylation analyzed by primer extension (SHAPE) utiliz...
- Title
- Detrimental brain inflammation and the role of the interleukin 10 family members
- Author
- Burmeister, Amanda
- Date Created
- 2019
- Subjects--Topical
- Biology
- Description
- Resident brain cells recognize pathogens and can initiate and/or regulate inflammation. Indeed, we have shown that stimulated glial cells rapidly produce inflammatory mediators, followed by the late production of anti-inflammatory cytokines such a...
- Title
- Developmental and light-entrained expression of melatonin and its relationship to the circadian clock in the sea anemone Nematostella vectensis
- Author
- Reitzel, Adam M., Peres, Rafael, Passamaneck, Yale
- Date Created
- 2014
- Subjects--Topical
- Gene expression, Biology
- Description
- Background: The primary hormone of the vertebrate pineal gland, melatonin, has been identified broadly throughout the eukaryotes. While the role for melatonin in cyclic behavior via interactions with the circadian clock has only been reported in v...
- Title
- Developmental expression of germline- and sex determination-related genes in the ctenophore Mnemiopsis leidyi
- Author
- Reitzel, Adam M., Pang, Kevin, Martindale, Mark Q.
- Date Created
- 2016
- Subjects--Topical
- Evolution (Biology), Biology
- Description
- Background: An essential developmental pathway in sexually reproducing animals is the specification of germ cells and the differentiation of mature gametes, sperm and oocytes. The germline genes vasa, nanos and piwi are commonly identified in prim...
- Title
- Diel patterning in the bacterial community associated with the sea anemone Nematostella vectensis
- Author
- Reitzel, Adam M., Leach, Whitney B., Carrier, Tyler J.
- Date Created
- 2019
- Subjects--Topical
- Gene expression, Biology
- Description
- Microbes can play an important role in the physiology of animals by providing essential nutrients, inducing immune pathways, and influencing the specific species that compose the microbiome through competitive or facilitatory interactions. The com...
- Title
- Disulfide-trapped CXCL12-CXCL4 Chemokine Heterodimers Prevent Breast Cancer Progression
- Author
- Nguyen, Khanh
- Date Created
- 2021
- Subjects--Topical
- Biology
- Description
- Triple negative breast cancers (TNBCs), i.e., 10-15% of diagnosed breast cancers, have a triple negative (Her/2-, ER- and PR-) phenotype and are the most aggressive subtype of breast cancer. TNBCs have a worst prognosis because of the high probabi...
- Title
- Dry Preservation of Germinal Vesicles: Development of a New Formulation to Preserve DNA Integrity Under Adverse Environmental Conditions
- Author
- Orozco Cabral, Joseph
- Date Created
- 2022
- Subjects--Topical
- Biology, Bioengineering
- Description
- Advances in the cryopreservation of genetic material has revolutionized human reproductive medicine and animal conservation efforts. Despite many successes, oocytes have been more challenging to cryopreserve than sperm. Their large size makes it d...
- Title
- EFFECT OF CADMIUM AND SEASONALITY ON CRITICAL TEMPERATURES OF AEROBIC METABOLISM IN EASTERN OYSTERS, Crassostrea virginica Gmelin 1791
- Author
- Bagwe, Rita
- Date Created
- 2012
- Subjects--Topical
- Biology
- Description
- Cadmium (Cd) and elevated temperatures are common stressors in estuarine and coastal environments affecting intertidal mollusks such as oysters. Cd and elevated temperature can raise the metabolic demands of oysters due to the increase cost of det...
- Title
- EFFECTS OF S-ADENOSYL-L-METHIONINE ON COLLAGEN EXPRESSION IN ACTIVATED HEPATIC STELLATE CELLS
- Author
- Thompson, Kyle
- Date Created
- 2009
- Subjects--Topical
- Biology, Cytology
- Description
- Liver fibrosis is defined as the excessive accumulation of extracellular matrix (ECM) components, which can disrupt the normal liver microcirculation and lead to injury. Unresolved, hepatic fibrosis can progress to cirrhosis, an end-state liver di...
- Title
- EFFECTS OF SILIBININ ON ETHANOL-MEDIATED HEPATOCELLULAR CARCINOMA PROGRESSION IN MALE AND FEMALE MICE
- Author
- Warner, Elizabeth
- Date Created
- 2011
- Subjects--Topical
- Biology
- Description
- Ethanol is a significant risk for the development of hepatic cirrhosis and progression to hepatocellular carcinoma (HCC). While females are more susceptible to the deleterious effects of ethanol, the incidence of cirrhosis and HCC is significantly...
- Title
- ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
- Author
- Okwei, Elleansar
- Date Created
- 2016
- Subjects--Topical
- Chemistry, Biology, Biochemistry
- Description
- The fight against bacterial infection is one of the most important branches of modern medicine. Due to the emergence of strains of antibiotic-resistant bacteria, researchers have been presented with complex challenges in an effort to combat these ...
- Title
- EVALUATING BIOFLAVONOID INDUCED DNA DOUBLE-STRAND BREAKS AND CHROMOSOMAL TRANSLOCATIONS
- Author
- Goodenow, Donna
- Date Created
- 2020
- Subjects--Topical
- Biology
- Description
- Dietary bioflavonoids are a class of chemical compounds found in soy, fruits, vegetables, tea, coffee, wine, and dietary supplements. They are separated into 12 different sub-classes based upon their structure, however only six are dietarily relev...