Search results | J. Murrey Atkins Library

Title: The induction of type-I interferon responses in primary osteoblasts following staphylococcus aureus infection
Author: Furr, Kelli
Date Created: 2022
Subjects--Topical: Biology
Description: Osteomyelitis is a serious bacterial infection of bone that is associated with progressive inflammatory tissue damage. This condition commonly affects the long bones of children along with the vertebrae and pelvis of adults. Staphylococcus aureus,...

Title: Assessing the impact of temperature on population-specific gene expression of a model estuarine cnidarian, Nematostella vectensis
Author: Klock, Amy
Date Created: 2020
Subjects--Topical: Biology
Description: Temperature is a critical environmental factor that affects all living organisms. Climate change is resulting in rising global temperatures with marine environments being especially vulnerable. My study aimed to elucidate the temperature-dependent...

Title: BIOFLAVONOIDS GENISTEIN AND QUERCETIN TRIGGER ALTERNATIVE END JOINING PATHWAY OF DNA REPAIR
Author: GHOSH, ANINDITA
Date Created: 2019
Subjects--Topical: Biology
Description: Faithful repair of chromosomal double-strand breaks (DSBs) is crucial to genome stability and normal cell survival and proliferation. During normal metabolic processes and especially following exposure to DNA damaging agents including irradiation,...

Title: Apoptotic T-cell derived microparticles containing sonic hedgehog modulate endothelial cell functions in inflammation via rho kinase pathway
Author: Attal, Neha
Date Created: 2019
Subjects--Topical: Biology
Description: Impaired vascular regulation as a result of endothelial dysfunction is a major determinant of sepsis-associated liver failure. We have previously shown that inhibition of one signaling molecule rho-kinase (ROCK) predominantly restores endothelial ...

Title: Dry Preservation of Germinal Vesicles: Development of a New Formulation to Preserve DNA Integrity Under Adverse Environmental Conditions
Author: Orozco Cabral, Joseph
Date Created: 2022
Subjects--Topical: Biology, Bioengineering
Description: Advances in the cryopreservation of genetic material has revolutionized human reproductive medicine and animal conservation efforts. Despite many successes, oocytes have been more challenging to cryopreserve than sperm. Their large size makes it d...

Title: EFFECTS OF SILIBININ ON ETHANOL-MEDIATED HEPATOCELLULAR CARCINOMA PROGRESSION IN MALE AND FEMALE MICE
Author: Warner, Elizabeth
Date Created: 2011
Subjects--Topical: Biology
Description: Ethanol is a significant risk for the development of hepatic cirrhosis and progression to hepatocellular carcinoma (HCC). While females are more susceptible to the deleterious effects of ethanol, the incidence of cirrhosis and HCC is significantly...

Title: IDENTIFICATION OF EPITHELIAL OVARIAN TUMOR SPECIFIC APTAMERS THAT BIND AND INTERNALIZE INTO TARGET CELLS
Author: Benedetto, Gregory
Date Created: 2015
Subjects--Topical: Chemistry, Biology
Description: New clinical tools that aid in the early diagnosis of ovarian malignancies will significantly help reduce mortality and improve current long-term survival rates. The objective of the work presented here was to identify ovarian tumor specific singl...

Title: Hepatic Stellate Cell Transdifferentiation: Pro-fibrogenic Effectors
Author: Lakner, Ashley
Date Created: 2011
Subjects--Topical: Molecular biology, Biology
Description: Hepatic fibrosis is a significant cause of morbidity and mortality worldwide and can be described as exacerbated wound-healing marked by excessive deposition of extracellular matrix components, predominantly type I collagen. Chronic injury stimula...

Title: Hydrogen Sulfide Modulates Hepatic Oxygen Availability and Microcirculation during Sepsis
Author: Norris, Eric
Date Created: 2012
Subjects--Topical: Biology, Physiology
Description: A mismatch between O_{2_{supply and demand leads to the development of tissue hypoxia which contributes to hepatic dysfunction and injury during sepsis. Previously, we reported that hepatic microcirculatory failure is a major contributor to hypoxia a...}}

Title: GLYCOGEN ENHANCEMENT AUGMENTS OVERLOAD-INDUCED PROTEIN SYNTHESIS, GROWTH, AND MYOGENESIS IN AGED SKELETAL MUSCLE
Author: Lawrence, Marcus
Date Created: 2017
Subjects--Topical: Biology, Kinesiology, Physiology
Description: ABSTRACTMARCUS MICHAEL LAWRENCE. Glycogen Enhancement Augments Overload-Induced Protein Synthesis, Growth, and Myogenesis in Aged Skeletal Muscle. (Under the direction of DR. SCOTT E. GORDON)Age-related skeletal muscle (SkM) wasting is associated ...

Title: Fungal Treatments for Lignocellulosic Bioconversion
Author: Giles, Richard
Date Created: 2013
Subjects--Topical: Power resources, Biology
Description: Four studies were conducted to develop an innovative application of fungal biopulping technologies to improve commercialization of lignocellulosic ethanol biofuel production using sustainable waste products. The first study focused on evaluation a...

Title: Genomic Dissection of Complex Trait Variation in Wild Soybean, Glycine soja
Author: Kofsky, Janice
Date Created: 2019
Subjects--Topical: Biology, Bioinformatics, Plant diseases
Description: There is a considerable demand for crop improvement, especially considering the growing population, continuing climatic fluctuations, and rapidly evolving plant pests and pathogens. Crop wild relatives hold great potential in providing beneficial ...

Title: Genetic and metabolomic characterization of wild soybean in response to soybean cyst nematode (Heterodera glycine)
Author: Mittal, Neha
Date Created: 2020
Subjects--Topical: Bioinformatics, Agriculture
Description: Crops harvesting ensure human survival on earth. However, sustainable crop production is challenging because of continuous biotic stresses caused by different pests (e.g., nematodes, bacteria, fungi, viruses, and insects). Soybean (Glycine max) is...

Title: MACROPHAGES EXPRESSING NEUROPILIN-1 AND BREAST TUMOR PROGRESSION
Author: Helms, Rachel
Date Created: 2015
Subjects--Topical: Biology
Description: Human breast carcinoma is the most commonly diagnosed cancer in women in the United States with patient mortality primarily resulting from metastasis of breast cancer cells to distant organs. Immune cells, including macrophages, are involved in ca...

Title: HOST FACTORS CONTROLLING VIRUS INFECTION: IMPLICATIONS FOR ANTIVIRALS AND VIROTHERAPY
Author: Shah, Nirav
Date Created: 2013
Subjects--Topical: Virology, Oncology
Description: Viruses are obligate intracellular parasites rely heavily on host components and pathways for their replication. Studying different cellular factors affecting viral infection can enable us to identify novel drug targets, improve current antiviral ...

Title: MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Author: Grover, Priyanka
Date Created: 2019
Subjects--Topical: Biology
Description: In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...

Title: Long-term study of changes in microbiota in a Cystic Fibrosis patient
Author: Stokell, Joshua
Date Created: 2013
Subjects--Topical: Biology, Microbiology
Description: Application of culture-independent techniques have revealed the presence of more types of bacteria than were previously thought, which led to the current description of Cystic Fibrosis (CF) being a polymicrobial disease. We know this polymicrobial...

Title: MOLECULAR MECHANISMS OF RESISTANCE OF PANCREATIC DUCTAL ADENOCARCINOMA CELLS TO ONCOLYTIC VESICULAR STOMATITIS VIRUS
Author: Felt, Sebastien
Date Created: 2017
Subjects--Topical: Molecular biology, Virology, Cytology
Description: Oncolytic virus (OV) therapy is an anticancer therapy using replication-competent viruses selectively infecting, replicating in and killing cancer cells. Human pancreatic ductal adenocarcinoma (PDAC) cell lines are highly heterogeneous in their pe...

Title: Mechanisms of acclimation and adaptation in the sea urchin Echinometra sp. EZ
Author: Ketchum, Remi
Date Created: 2017
Subjects--Topical: Biology
Description: Climate change has resulted in warming of coastal aquatic habitats around the world at almost every latitude, threatening ecosystems with a significant loss in biodiversity and occurring at a rate that may exceed species’ ability to adapt. Underst...

Title: INVESTIGATING THE ECOLOGICAL, PATHOGENIC, AND DORMANT LIFESTYLES OF THE ESTUARINE BACTERIUM, VIBRIO VULNIFICUS
Author: Williams, Tiffany
Date Created: 2015
Subjects--Topical: Microbiology, Bioinformatics
Description: Vibrio vulnificus is ubiquitous in estuarine and coastal waters worldwide and associates naturally with a variety of aquatic organisms. Notably, it is a highly invasive human pathogen capable of causing septicemia and multi-organ failure in person...