Characterizing the diversity of heat shock proteins in Nematostella vectensis and Saccharomyces cerevisiae

Search for this publication on Google Scholar
Alexander, W., Reitzel, A. M., & Truman, A. (2022). Characterizing the diversity of heat shock proteins in Nematostella vectensis and Saccharomyces cerevisiae. Unc Charlotte Undergraduate Research Conference.
Download PDF

Analytics

27 views ◎
7 downloads ⇓


Description

Heat shock proteins (HSPs) are a highly conserved family of proteins critical to both environmental stress response and cellular function under normal conditions. More specifically HSPs are chaperone proteins that work to refold other misfolded proteins. Data suggests that HSPs have neuroprotective effects against protein aggregation diseases such as Alzheimer's. Previous research indicates that HSP70 has evolved multiple isoforms or variants in organisms such as the sea anemone Nematostella vectensis and Saccharomyces cerevisiae budding yeast. While the presence of these isoforms is established, the function and evolutionary history is not fully understood. The purpose of this research is to contribute
towards a better understanding of the HSP70 isoforms. Presented at the 2022 UNC Charlotte Undergraduate Research Conference.

Details
Title

Characterizing the diversity of heat shock proteins in Nematostella vectensis and Saccharomyces cerevisiae

Author(s)

Alexander, William
Reitzel, Adam M.
Truman, Andrew

UNC Charlotte Affiliate Type

Undergraduate

Extent

1 online resource

Date Created

2022

Material Type

Conference poster

Genre

conference proceedings

Resource Type

text

Abstract

Heat shock proteins (HSPs) are a highly conserved family of proteins critical to both environmental stress response and cellular function under normal conditions. More specifically HSPs are chaperone proteins that work to refold other misfolded proteins. Data suggests that HSPs have neuroprotective effects against protein aggregation diseases such as Alzheimer's. Previous research indicates that HSP70 has evolved multiple isoforms or variants in organisms such as the sea anemone Nematostella vectensis and Saccharomyces cerevisiae budding yeast. While the presence of these isoforms is established, the function and evolutionary history is not fully understood. The purpose of this research is to contribute towards a better understanding of the HSP70 isoforms. Presented at the 2022 UNC Charlotte Undergraduate Research Conference.

Subjects--Topics

Heat shock proteins
Biology

Is Part Of

UNC Charlotte undergraduate research conference

Language

English

Permalink

http://hdl.handle.net/20.500.13093/work:299

Rights

This item may be protected by copyright and other related rights. Atkins Library provides access to this item for educational and research purposes only; other uses require the permission of the copyright holder.