On-street bike lanes have been increasingly visible in the City of Charlotte but rarely utilized. The Charlotte Bikes bicycle program, adopted by City Council May, 2017, proposed that bicycle facilities implemented on arterials should be separated from traffic by a concrete barrier or grass buffer. However, providing on-street bike lanes and separating from traffic alone may not attract residents to use cycle as a mode of transportation. This could be attributed to roughly 30% of all bike-related crashes that generally occur at urban intersections. Therefore, this research seeks to improve safety at intersections. The focus is primarily to evaluate the safety and operational effects of Protected Intersection design on cyclists’ safety at intersections.The Protected Intersection design was modeled and evaluated at the intersection of Tyvola Rd and South Blvd in south Charlotte. Traffic was modeled on the existing and proposed intersections using PTV VISSIM microscopic simulation software under conditions of zero percent bikes to fifteen percent bikes. Safety was then analyzed using Surrogate Safety Assessment Model (SSAM), and conflicts were defined as a 1.5 second intersection of two or more trajectories. The results indicate as much as an 80% reduction in bicycle-related crossing-type conflicts. It was also found that atmospheric emissions can be reduced by as much as 40% by offering separate right of way for bicycles, versus placing bicycles on a shared lane with motorists. The results support the hypothesis that the Protected Intersection significantly reduces conflicts at intersections, and therefore improves safety.